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Article
Consistent efficacy outcomes between phase 2 and phase 3 trials in Crohn’s disease or ulcerative colitis in adults: a meta-analysis
The approval of novel biologic agents and small molecules for the treatment of Crohn's disease (CD) and ulcerative colitis (UC) is dependent on phase 3 randomized controlled trials (RCTs). However, these trial...
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Article
Open AccessFine map** of TFL, a major gene regulating fruit length in snake gourd (Trichosanthes anguina L)
Fruit length is a crucial agronomic trait of snake gourd (Trichosanthes anguina L); however, genes associated with fruit length have not been characterised. In this study, F2 snake gourd populations were generate...
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Article
Open AccessPlasma campesterol and ABCG5/ABCG8 gene loci on the risk of cholelithiasis and cholecystitis: evidence from Mendelian randomization and colocalization analyses
The causal relationships between plasma metabolites and cholelithiasis/cholecystitis risks remain elusive. Using two-sample Mendelian randomization, we found that genetic proxied plasma campesterol level showe...
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Article
A Review of High-Strength Aluminum-Copper Alloys Fabricated by Wire Arc Additive Manufacturing: Microstructure, Properties, Defects, and Post-processing
Wire arc additive manufacturing (WAAM) techniques have been gaining increasing attention in the contemporary manufacturing sector due to their advantages in economically producing large-sized metallic componen...
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Article
Microstructure Evolution and Mechanical Properties of Ti and Zr Micro-Alloyed Al-Cu Alloy Fabricated by Wire + Arc Additive Manufacturing
The inhomogeneous microstructure and mechanical property anisotropy of aluminum alloys fabricated by wire + arc additive manufacturing (WAAM) commonly have negative impacts on the applications of WAAM aluminum...
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Article
Biliary inflammation scoring for immunoglobulin G4-related sclerosing cholangitis: an endoscopic approach with endoscopic ultrasound
The differential diagnosis of immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) and cholangiocarcinoma (CC) remains a clinical challenge. Imaging modalities play critical roles in the diagnosis of IgG...
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Chapter
Case Atlas and Illustrations: Stomach
Multiple well-differentiated adenocarcinoma, 0 IIc, depth of invasion M1, on the lower 1/3 of stomach.
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Article
Model to identify early-stage gastric cancers with deep invasion of submucosa based on endoscopy and endoscopic ultrasonography findings
Conventional endoscopy and endoscopic ultrasonography (EUS) are used to estimate the invasion depth of early-stage gastric cancers (EGCs), but estimates made by either technique are often inaccurate. We develo...
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Article
Seed priming in dry direct-seeded rice: consequences for emergence, seedling growth and associated metabolic events under drought stress
Drought stress encumbers the seed germination and delays seedling establishment in dry direct-seeded rice. Pot and field studies were carried out to ascertain the role of seed-priming on emergence, seedling gr...
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Article
Influence of the Ring Size on the Binding Ability of FTO Investigated by Fluorescence Spectroscopy
The fat mass and obesity associated protein (FTO) is a potential target for anti-obesity medicines. In this paper, we have synthesized two potential inhibitors for FTO, three-member-ring compound (W ...
