-
Article
Open AccessDevelopment and validation of an inflammatory biomarkers model to predict gastric cancer prognosis: a multi-center cohort study in China
Inflammatory factors have increasingly become a more cost-effective prognostic indicator for gastric cancer (GC). The goal of this study was to develop a prognostic score system for gastric cancer patients bas...
-
Article
Open AccessAssociation of adherence to the enhanced recovery after surgery pathway and outcomes after laparoscopic total gastrectomy
The current study used a composite outcome to investigate whether applying the ERAS protocol would enhance the recovery of patients undergoing laparoscopic total gastrectomy (LTG).
-
Article
Open AccessPhysical and psychological correlates of somatic symptom in patients with functional constipation: a cross-sectional study
The symptoms of functional constipation (FC) were obviously affected by mental symptoms, which was consistent with somatic symptoms. However, the characteristics of FC patients with somatic symptom remains une...
-
Article
Open AccessIdentification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire
Immunotherapeutic strategies aimed at enhancing tumor cell killing by tumor-specific T cells hold great potential for reducing tumor burden and prolonging survival of cancer patients. Although many potential t...
-
Article
Open AccessMultilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer
Diffuse-type gastric cancer (DGC) and intestinal-type gastric cancer (IGC) are the major histological types of gastric cancer (GC). The molecular mechanism underlying DGC and IGC differences are poorly underst...
-
Chapter and Conference Paper
No-Fuzz: Efficient Anti-fuzzing Techniques
Fuzzing is an automated software testing technique that has achieved great success in recent years. While this technique allows developers to uncover vulnerabilities avoiding consequent issues (e.g., financial...
-
Article
Open AccessPostoperative short-term use of the nonsteroidal anti-inflammatory drug flurbiprofen did not increase the anastomotic leakage rate in patients undergoing elective gastrointestinal surgery—a retrospective cohort study
Flurbiprofen has been one of the most commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) in China and other Asian countries for perioperative multimodal analgesia in recent years, yet its association ...
-
Chapter and Conference Paper
Experimental Study on Peaking Performance of 145 MW Circulating Fluidized Bed Boiler Unit with Retrofitting for Low-Vacuum Heat Supply
The peaking performance of 145 MW circulating fluidized bed (CFB) boiler unit with retrofitting for low-vacuum heat supply were studied in this article. Peaking depth, peaking rate, tube wall temperature of su...
-
Article
Proteomics provides individualized options of precision medicine for patients with gastric cancer
While precision medicine driven by genome sequencing has revolutionized cancer care, such as lung cancer, its impact on gastric cancer (GC) has been minimal. GC patients are routinely treated with chemotherapy...
-
Article
Open AccessHSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance
Pseudouridine synthase (PUS) 7 is a member of the PUS family that catalyses pseudouridine formation. It has been shown to be involved in intellectual development and haematological malignancies. Nevertheless, ...
-
Article
Open AccessWidespread and tissue-specific expression of endogenous retroelements in human somatic tissues
Endogenous retroelements (EREs) constitute about 42% of the human genome and have been implicated in common human diseases such as autoimmunity and cancer. The dominant paradigm holds that EREs are expressed i...
-
Article
Perioperative Complications and Outcomes after Intestinal Autotransplantation for Neoplasms Involving the Superior Mesenteric Artery
Intestinal autotransplantation (IATx) is a novel surgical technique for neoplasms arising from the pancreas, duodenum, mesentery, or retroperitoneum with involvement of the superior mesenteric artery (SMA). Th...
-
Article
Open AccessDisease characteristics and treatment patterns of Chinese patients with metastatic colorectal cancer: a retrospective study using medical records from China
Colorectal cancer (CRC) is the third most prevalent cancer in China but few large-scale studies were conducted to understand CRC patients. The current study is aimed to gain a real-world perspectives of CRC pa...
-
Chapter and Conference Paper
On the Accuracy of Measured Proximity of Bluetooth-Based Contact Tracing Apps
A large number of Bluetooth-based mobile apps have been developed recently to help tracing close contacts of contagious COVID-19 individuals. These apps make decisions based on whether two users are in close p...
-
Chapter and Conference Paper
A Study of the Privacy of COVID-19 Contact Tracing Apps
The COVID-19 pandemic has spread across the globe and resulted in substantial loss of lives and livelihoods. To effectively fight this pandemic, many digital contact tracing mobile apps have been developed. Un...
-
Article
Structural changes in brain regions involved in executive-control and self-referential processing after sleeve gastrectomy in obese patients
Obesity-related brain gray (GM) and white matter (WM) abnormalities have been reported in regions associated with food-intake control and cognitive-emotional regulation. Bariatric surgery (BS) is the most effe...
-
Article
Open AccessIdentification of hub genes and therapeutic drugs in esophageal squamous cell carcinoma based on integrated bioinformatics strategy
Esophageal squamous cell carcinoma (ESCC) is one of leading malignant cancers of gastrointestinal tract worldwide. Until now, the involved mechanisms during the development of ESCC are largely unknown. This st...
-
Article
Ghrelin reductions following bariatric surgery were associated with decreased resting state activity in the hippocampus
Laparoscopic sleeve gastrectomy (LSG) is an effective bariatric surgery to treat obesity, and involves removal of the gastric fundus where ghrelin is mainly produced. Ghrelin stimulates appetite and regulates ...
-
Article
Surgical and Long-Term Survival Outcomes After Laparoscopic and Open Total Gastrectomy for Locally Advanced Gastric Cancer: A Propensity Score-Matched Analysis
To compare the surgical and long-term survival outcomes of laparoscopic and open total gastrectomy (OTG) for locally advanced gastric cancer (AGC).
-
Article
Reciprocal regulations between miRNAs and HIF-1α in human cancers
Hypoxia inducible factor-1α (HIF-1α) is a central molecule involved in mediating cellular processes. Alterations of HIF-1α and hypoxically regulated microRNAs (miRNAs) are correlated with patients’ outcome in ...
