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Article
Open AccessMetabotropic signaling within somatostatin interneurons controls transient thalamocortical inputs during development
During brain development, neural circuits undergo major activity-dependent restructuring. Circuit wiring mainly occurs through synaptic strengthening following the Hebbian “fire together, wire together” precep...
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Article
Open AccessVariational AdaBoost knowledge distillation for skin lesion classification in dermatology images
Knowledge Distillation has shown promising results for classifying skin lesions in dermatology images. Traditional knowledge distillation typically involves the student model passively mimicking the teacher mo...
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Article
Open AccessPredictive strategies for oocyte maturation in IVF cycles: from single indicators to integrated models
Accurate prediction of oocyte maturation is a critical determinant of success in in vitro fertilization-embryo transfer (IVF-ET) procedures. This review provides a comprehensive analysis of the various predict...
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Article
Open AccessFunctional genetic variants of GEN1 predict overall survival of Chinese epithelial ovarian cancer patients
Inherited variations in DNA double-strand break (DSB) repair pathway are known to influence ovarian cancer occurrence, progression and treatment response. Despite its significance, survival-associated genetic ...
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Article
PABPC1 silencing inhibits pancreatic cancer cell proliferation and EMT, and induces apoptosis via PI3K/AKT pathway
Pancreatic cancer is difficult to manage owing to the challenges involved in its treatment and nursing. This study aimed to clarify the roles and mechanisms of action of Poly (A)-binding protein cytoplasmic 1 ...
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Article
Extracellular volume fraction derived from dual-energy CT: a potential predictor for acute pancreatitis after pancreatoduodenectomy
To investigate the value of extracellular volume (ECV) fraction and fat fraction (FF) derived from dual- energy CT (DECT) for predicting postpancreatectomy acute pancreatitis (PPAP) after pancreatoduodenectomy...
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Article
Added value of DCER-features to clinicopathologic model for predicting metachronous metastases in rectal cancer patients
The study aimed to investigate whether dynamic contrast-enhanced MRI parameters and preoperative radiological features (DCER-Features) add value to the clinicopathologic model for predicting metachronous metas...
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Article
Pretreatment Absolute Immature Platelet Count is a Promising Predictor of Response to Short-Term Dexamethasone Monotherapy or Combination Therapy in Newly Diagnosed Adult Primary Immune Thrombocytopenia
Reliable indicators that can predict drug responsiveness in primary immune thrombocytopenia (ITP) patients are urgent. We aimed to establish a reference interval of percentage of immature platelet fraction (IP...
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Article
Beneficial effect of oxygen-ion conductor infiltration on the electrocatalytic properties of a heavily strontium-doped lanthanum nickelate Ruddlesden-Popper SOFC cathode
The microstructure and electrocatalytic activity for oxygen reduction reaction of La1.2Sr0.8NiO4-δ electrodes were examined as a function of electrode thickness. The length of catalytically active region and opti...
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Article
Open AccessPhotoheterotroph improved the growth and nutrient levels of Chlorella vulgaris and the related molecular mechanism
Microalgae are rich in fatty acids, proteins, and other nutrients, which have gained the general attention of researchers all over the world. For the development of Chlorella vulgaris in food and feed industry, t...
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Article
Noninvasive identification of SOX9 status using radiomics signatures may help construct personalized treatment strategy in hepatocellular carcinoma
To develop and validate a radiomics-based model for predicting SOX9-positive hepatocellular carcinoma (HCC) using preoperative contrast-enhanced computed tomography (CT) images.
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Article
Clinical and Pathologic Predictors of Tumor Deposits in Colorectal Cancer
Tumor deposits (TDs) are a special metastatic pattern of colorectal cancer (CRC). This study aims to explore the pathological characteristics of TD and find out the risk factors of TD in CRC.
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Article
Open AccessCharging modulation of the pyridine nitrogen of covalent organic frameworks for promoting oxygen reduction reaction
Covalent organic frameworks (COFs) are ideal templates for constructing metal-free catalysts for the oxygen reduction reaction due to their highly tuneable skeletons and controllable porous channels. However, ...
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Article
Open AccessAn integrated data analysis reveals distribution, hosts, and pathogen diversity of Haemaphysalis concinna
Haemaphysalis concinna, carrying multiple pathogens, has attracted increasing attention because of its expanded geographical range and significant role in disease transmission. This study aimed to identify the po...
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Article
Open AccessVirome diversity shaped by genetic evolution and ecological landscape of Haemaphysalis longicornis
Haemaphysalis longicornis is drawing attentions for its geographic invasion, extending population, and emerging disease threat. However, there are still substantial gaps in our knowledge of viral composition in r...
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Article
Repaglinide restrains HCC development and progression by targeting FOXO3/lumican/p53 axis
The recent focus on the roles of N-linked glycoproteins in carcinogenesis across various malignancies has prompted our exploration of aberrantly expressed glycoproteins responsible for HCC progression and pote...
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Article
Effects of thinning and understory removal on water use efficiency of Pinus massoniana: evidence from photosynthetic capacity and stable carbon isotope analyses
Understanding the relationship between forest management and water use efficiency (WUE) is important for evaluating forest adaptability to climate change. However, the effects of thinning and understory remova...
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Article
Hydrothermal treatment of furfural and sugar monomers and oligomers: a model-compound approach to probe the cross-polymerization reactions in heating bio-oil
The high tendency of bio-oil towards polymerization renders bio-oil with the application as the precursor for carbon materials. However, the pathway of the cross-polymerization of the major components of bio-o...
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Article
Fe3+ Sensing Based on Hydrogel Optical Fiber Doped with Nitrogen Carbon Dots
In this paper, a nontoxic and biocompatible hydrogel optic fiber Fe3+ sensor is presented. Nitrogen carbon dots (NCDs) as fluorescence indicators are prepared by a one-step hydrothermal method using citric acid a...
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Article
Open AccessEpidemiological behaviour and interventions of malaria in Niger, 2010–2019: a time-series analysis of national surveillance data
Malaria remains a significant public health concern in Niger, with the number of cases increasing from 592,334 in 2000 to 3,138,696 in 2010. In response, a concerted campaign against the disease has been initi...
