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Article
Ten-year trends in surgical management of 1207 congenital scoliosis
To report and analyze development trends in the surgical treatment of congenital scoliosis (CS) in a large CS cohort over a 10-year period.
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Chapter
Hybrid Technique: Apical VCR and Growing Rod Combination for Severe Curves
Severe and rigid early onset scoliosis (EOS) is a pediatric condition that can lead to progressive deformities and impaired cardiopulmonary function, and thus early surgical intervention is necessary. Techniqu...
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Article
Open AccessTranexamic acid given into wound reduces postoperative drainage, blood loss, and hospital stay in spinal surgeries: a meta-analysis
Although intravenous tranexamic acid administration (ivTXA) has prevailed in clinical antifibrinolytic treatment, whether it increases thromboembolic risks has remained controversial. As a potent alternative t...
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Article
Open AccessChondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification
Ankylosing spondylitis (AS) is chronic inflammatory arthritis with a progressive fusion of axial joints. Anti-inflammatory treatments such as anti-TNF-α antibody therapy suppress inflammation but do not effect...
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Article
Open AccessSPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells
Adolescent idiopathic scoliosis (AIS) is a complex, three-dimensional deformity of the spine that commonly occurs in pubescent girls. Decreased osteogenic differentiation and aberrant melatonin signalling have...
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Article
Long noncoding RNA lncAIS downregulation in mesenchymal stem cells is implicated in the pathogenesis of adolescent idiopathic scoliosis
Adolescent idiopathic scoliosis (AIS) is a complex, three dimensional deformity of the spine that commonly occurs in pubescent girls. Abnormal osteogenic differentiation of mesenchymal stem cells (MSCs) is imp...
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Article
Open AccessTranexamic Acid in Reducing Gross Hemorrhage and Transfusions of Spine Surgeries (TARGETS): study protocol for a prospective, randomized, double-blind, non-inferiority trial
Tranexamic acid (TXA) has been routinely delivered in multisegmental spinal decompression and bone graft fusion surgeries with satisfactory outcomes in minimizing gross blood loss and transfusion demands. Howe...
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Article
Open AccessA randomized controlled trial on the effects of collagen sponge and topical tranexamic acid in posterior spinal fusion surgeries
This is a randomized controlled trial research to assess the hemostatic efficacy of gelatin sponge, collagen sponge, and topical use of tranexamic acid (TXA) on postoperative blood loss in posterior spinal fus...
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Article
Open AccessA randomized controlled trial on effects of different hemostatic sponges in posterior spinal fusion surgeries
Spinal fusion surgery is associated with significant blood loss, which may result in potential clinical complications, it is necessary to take safe and effective measures to reduce blood loss in surgery. We pe...
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Article
Intra-operative MEP monitoring can work well in the patients with neural axis abnormality
To explain the intra-operative transcranial motor evoked potential (MEP) monitoring can work well in patients with neural axis abnormality (NAA).
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Article
Prognostic value of intraoperative MEP signal improvement during surgical treatment of cervical compressive myelopathy
The purpose of the current study was to evaluate the prognostic value of intraoperative improved transcranial motor evoked potential (MEP) after cervical cord decompressive surgery for cervical compressive mye...
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Article
Multiple cervical hemivertebra resection and staged thoracic pedicle subtraction osteotomy in the treatment of complicated congenital scoliosis
To present our experience of staged correction with multiple cervical hemivertebra resection and thoracic pedicle subtraction osteotomy (PSO) treating a rare and complicated congenital scoliosis.
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Article
One-stage posterior-only lumbosacral hemivertebra resection with short segmental fusion: a more than 2-year follow-up
Lumbosacral hemivertebra poses a unique problem because it can cause gross imbalance and progressive compensatory thoracolumbar deformity. Previous studies have reported lumbosacral hemivertebra resection thro...
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Article
Multicentric epidemiologic study on six thousand three hundred and ninety five cases of femoral head osteonecrosis in China
Osteonecrosis of femoral head (ONFH) is a common joint disease with high morbidity in mainland China. We performed a retrospective case investigation based on the widest range of patients ever to reveal the de...
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Article
Non-continuous versus continuous wound drainage after total knee arthroplasty: a meta-analysis
So far, controversy still exists regarding the use of non-continuous or continuous wound drainage after total knee arthroplasty. The aim of this study was to assess the efficacy and safety of these two drainag...
