-
Article
Open AccessThe adhesion-GPCR ADGRF5 fuels breast cancer progression by suppressing the MMP8-mediated antitumorigenic effects
ADGRF5 (GPR116) has been identified as a facilitator of breast cancer cell migration and metastasis, yet the underlying mechanisms remain largely elusive. Our current study reveals that the absence of ADGRF5 i...
-
Chapter and Conference Paper
Psychological Service Design: From Consulting Space to Experience Place
Through case analysis of changes in mental health counseling methods both domestically and internationally, a multidimensional quadrant model for the design turn of psychological counseling centers is abstract...
-
Article
Time Regularity for Local Weak Solutions of the Heat Equation on Local Dirichlet Spaces
We study the time regularity of local weak solutions of the heat equation in the context of local regular symmetric Dirichlet spaces. Under two basic and rather minimal assumptions, namely, the existence of ce...
-
Article
Open AccessBioinspired trimesic acid anchored electrocatalysts with unique static and dynamic compatibility for enhanced water oxidation
Layered double hydroxides are promising candidates for the electrocatalytic oxygen evolution reaction. Unfortunately, their catalytic kinetics and long-term stabilities are far from satisfactory compared to th...
-
Article
Open AccessPropofol inhibits colon cancer cell stemness and epithelial-mesenchymal transition by regulating SIRT1, Wnt/β-catenin and PI3K/AKT/mTOR signaling pathways
Propofol is a common sedative-hypnotic drug used for general anesthesia. Recent studies have drawn attention to the antitumor effects of propofol, but the potential mechanism by which propofol suppresses colon...
-
Article
Open AccessPrediction of the shear capacity of ultrahigh-performance concrete beams using neural network and genetic algorithm
Currently, concrete structures have increasingly higher requirements for the shear capacity of beams, and ultrahigh-performance concrete (UHPC) beams are increasingly widely used. To facilitate the design of U...
-
Article
Motion of Lee–Yang Zeros
We consider the zeros of the partition function of the Ising model with ferromagnetic pair interactions and complex external field. Under the assumption that the graph with strictly positive interactions is co...
-
Article
Low delay flexible paper-based electrode for capacitive sensor filled through carbon-based materials
Paper-based sensors have good application prospects due to their flexibility and environmental protection. However, paper-based materials are difficult to balance both conductivity and flexibility. This paper ...
-
Article
LncRNA Riken Attenuated Sevoflurane-Induced Neuroinflammation by Regulating the MicroRNA-101a/MKP-1/JNK Pathway
The induction of anesthesia in children makes its safety one of the most important global health problems. Neuroinflammation contributes to anesthesia-induced neurotoxicity in young individuals. However, the m...
-
Article
Open AccessCigarette Smoke-Induced Pulmonary Inflammation and Autophagy Are Attenuated in Ephx2-Deficient Mice
Cigarette smoke (CS) increases the risk of chronic obstructive pulmonary disease (COPD) by causing inflammation, emphysema, and reduced lung function. Additionally, CS can induce autophagy which contributes to...
-
Article
Open AccessPolydatin protects the respiratory system from PM2.5 exposure
Atmospheric particle is one of the risk factors for respiratory disease; however, their injury mechanisms are poorly understood, and prevention methods are highly desirable. We constructed artificial PM2.5 (aPM2....
-
Chapter and Conference Paper
RGraph: Generating Reference Graphs for Better Machine Translation Evaluation
Statistical machine translation systems perform parameter learning (i.e. training) basing on automatic translation evaluation methods, which usually evaluate the translation quality according to one or more hu...
-
Article
Open AccessGSTM1 and GSTT1 polymorphisms contribute to renal cell carcinoma risk: evidence from an updated meta-analysis
Emerging evidences suggest that GSTM1 and GSTT1 are involved in the detoxification of carcinogens and polymorphisms in this gene that result in a loss of enzyme activity may increase the risk of renal cell carcin...
-
Article
Vam3, a resveratrol dimer, inhibits cigarette smoke-induced cell apoptosis in lungs by improving mitochondrial function
To investigate the effects of Vam3 (a resveratrol dimer extracted from Vitis amurensis Rupr) on cigarette smoke (CS)-induced cell apoptosis in lungs in vitro and in vivo and the underlying mechanisms of action.
-
Article
Multi-allergen Challenge Stimulates Steriod-Resistant Airway Inflammation via NF-κB-Mediated IL-8 Expression
Neutrophilic airway inflammation associated with multiple allergens has been related to steroid-resistant asthma. However, most animal models use only one allergen, which cannot simulate asthma closely as seen...
-
Article
Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy
To appraise the efficacy of Vam3 (Amurensis H), a dimeric derivative of resveratrol, at inhibiting cigarette smoke-induced autophagy.
-
Article
Analysis of lung cancer incidence and mortality in Tian**
Verification of the cases of lung cancer, from Tian** Cancer Registration System in 1981 – 1987, was conducted. It was suggested that lung cancer incidence and mortality had increased and ranked first among v...
