Analog Circuits and Signal Processing
Volume 0 / 2010 to Volume 131 / 2016
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Article
Open AccessDrug screening on digital microfluidics for cancer precision medicine
Drug screening based on in-vitro primary tumor cell culture has demonstrated potential in personalized cancer diagnosis. However, the limited number of tumor cells, especially from patients with early stage ca...
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Book Series
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Book
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Chapter
Power-Efficient RF and mm-Wave VCOs/PLL
Almost every electronic system demands a clock signal with high spectral purity. Wireless or wireline systems typically rely on two approaches to enhance the data rate: (1) employing a denser modulation scheme...
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Chapter
Integrated Energy Harvesting Interfaces
Exploiting renewable energy sources is essential to ensure perpetual system operation of Internet of Things (IoT) devices. With the ever growing demands for higher level of integration and functionality, highl...
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Chapter
High-Performance SAW-Less TDD/FDD RF Front-Ends
In order to develop multiband cellular radios at low cost, the rekindled on-chip N-path switched-capacitor filter is a promising replacement of the off-chip SAW (surface acoustic wave) filters, due to its prop...
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Chapter
Ultra-Low-Voltage Clock References
Clock references are indispensable circuit modules. The Internet of Things (IoT) devices, in particular, usually require a reference with high spectral purity for the phase-locked loop to generate the carrier ...
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Article
A 0.15-V, 44.73% PCE charge pump with CMOS differential ring-VCO for energy harvesting systems
This paper proposes a dynamic voltage frequency scaling technique (DVFS) for a CMOS differential bootstrapped ring-voltage controlled oscillator (DBRO), implemented in a 3-stage cross-coupled charge pump (CC-C...
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Article
Open AccessA digital microfluidic system with 3D microstructures for single-cell culture
Despite the precise controllability of droplet samples in digital microfluidic (DMF) systems, their capability in isolating single cells for long-time culture is still limited: typically, only a few cells can ...
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Article
Open AccessAuthor Correction: Drug screening of cancer cell lines and human primary tumors using droplet microfluidics
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
LampPort: a handheld digital microfluidic device for loop-mediated isothermal amplification (LAMP)
A major goal in the development of point-of-care (POC) devices is to build them as portable to provide a rapid and effective determination for disease pathogens. In nucleic acid testing, an optical detection s...
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Article
Ambient RF energy harvesting system: a review on integrated circuit design
This paper presents a comprehensive review of ambient RF energy harvester circuitry working on integrated circuits. The review covers 3 main blocks in an RF energy harvesting system implemented on chip. The bl...
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Chapter
Introduction
An essential part to evaluate the success of global health is the access to appropriate diagnostic tools [1]. A commendable diagnostic tool should be able to identify the disease occurred from the individuals ...
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Chapter
Conclusion and Outlook
In retrospect, this book firstly reviewed recent CMOS biosensors for in vitro diagnosis according to their transducing mechanisms (Chap. 2). Among these, NMR-based detec...
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Chapter
Electronic-Automated Micro-NMR Assay with DMF Device
We describe a micro-NMR relaxometer miniaturized into palm size and electronic-automated for multistep multi-sample chemical/biological diagnosis. The co-integration of microfluidic and microelectronic technologi...
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Chapter
Micro-NMR on CMOS for Biomolecular Sensing
In this chapter, we reported several portable nuclear magnetic resonance (NMR) systems implemented with silicon integrated circuits (IC). Being the initial researchers in the NMR on IC field, we firstly propos...
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Chapter
State-of-the-Art CMOS In Vitro Diagnostic Devices
CMOS technology enables low-cost and large-scale integration of transistors and physical sensing materials on tiny chips (e.g., <1 cm2), seamlessly combining the two key functions of biosensors: transducing and s...
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Chapter
One-Chip Micro-NMR Platform with B0-Field Stabilization
We report a micro-nuclear magnetic resonance (NMR) system compatible with multi-type biological/chemical lab-on-a-chip assays. Unified in a handheld scale (dimension, 14 × 6 × 11 cm3; weight, 1.4 kg), the system ...
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Article
Open AccessA digital microfluidic system for loop-mediated isothermal amplification and sequence specific pathogen detection
A digital microfluidic (DMF) system has been developed for loop-mediated isothermal amplification (LAMP)-based pathogen nucleic acid detection using specific low melting temperature (Tm) Molecular Beacon DNA prob...
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Article
Open AccessDrug screening of cancer cell lines and human primary tumors using droplet microfluidics
Precision Medicine in Oncology requires tailoring of therapeutic strategies to individual cancer patients. Due to the limited quantity of tumor samples, this proves to be difficult, especially for early stage ...
