Handheld Total Chemical and Biological Analysis Systems
Bridging NMR, Digital Microfluidics, and Semiconductors
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Ultra-Low-Voltage Clock References
Clock references are indispensable circuit modules. The Internet of Things (IoT) devices, in particular, usually require a reference with high spectral purity for the phase-locked loop to generate the carrier ...
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Chapter
Introduction
An essential part to evaluate the success of global health is the access to appropriate diagnostic tools [1]. A commendable diagnostic tool should be able to identify the disease occurred from the individuals ...
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Conclusion and Outlook
In retrospect, this book firstly reviewed recent CMOS biosensors for in vitro diagnosis according to their transducing mechanisms (Chap. 2). Among these, NMR-based detec...
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Electronic-Automated Micro-NMR Assay with DMF Device
We describe a micro-NMR relaxometer miniaturized into palm size and electronic-automated for multistep multi-sample chemical/biological diagnosis. The co-integration of microfluidic and microelectronic technologi...
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Chapter
Micro-NMR on CMOS for Biomolecular Sensing
In this chapter, we reported several portable nuclear magnetic resonance (NMR) systems implemented with silicon integrated circuits (IC). Being the initial researchers in the NMR on IC field, we firstly propos...
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State-of-the-Art CMOS In Vitro Diagnostic Devices
CMOS technology enables low-cost and large-scale integration of transistors and physical sensing materials on tiny chips (e.g., <1 cm2), seamlessly combining the two key functions of biosensors: transducing and s...
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Chapter
One-Chip Micro-NMR Platform with B0-Field Stabilization
We report a micro-nuclear magnetic resonance (NMR) system compatible with multi-type biological/chemical lab-on-a-chip assays. Unified in a handheld scale (dimension, 14 × 6 × 11 cm3; weight, 1.4 kg), the system ...
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Article
Systematic analysis and cancellation of kickback noise in a dynamic latched comparator
A dynamic latched comparator can suffer from three non-idealities: offset voltage, random noise and kickback noise. Specifically in an analog-to-digital converter (ADC) the kickback noise of a comparator can n...
