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  1. No Access

    Article

    Comparative Metabolomics and Network Pharmacology Analysis Reveal Shared Neuroprotective Mechanisms of Bacopa monnieri (L.) Wettst and Centella asiatica (L.) Urb

    Bacopa monnieri (L.) Wettst and Centella asiatica (L.) Urb., two nootropics, are recognized in Indian Ayurvedic texts. Studies have attempted to understand their action as memory enhancers and neuroprotectants, b...

    Sakshi Sanjay Parate, Shubham Sukerndeo Upadhyay, Amrutha S.… in Molecular Neurobiology (2024)

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    Article

    Meta-analysis of the serum/plasma proteome identifies significant associations between COVID-19 with Alzheimer’s/Parkinson’s diseases

    In recent years, we have seen the widespread devastations and serious health complications manifested by COVID-19 globally. Although we have effectively controlled the pandemic, uncertainties persist regarding...

    Althaf Mahin, Sreelakshmi Pathappillil Soman… in Journal of NeuroVirology (2024)

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    Article

    A network map of GDNF/RET signaling pathway in physiological and pathological conditions

    Glial cell line-derived neurotrophic factor (GDNF) signals through a multi-component receptor system predominantly consisting of glycosyl-phosphatidylinositol-anchored GDNF family receptor alpha-1 (GFRα1) and ...

    Praseeda Mol, Rex Devasahayam Arokia Balaya… in Journal of Cell Communication and Signaling (2023)

  4. No Access

    Article

    A complete map of the Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) signaling pathway

    Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) is a serine/threonine-protein kinase belonging to the Ca2+/calmodulin-dependent protein kinase subfamily. CAMKK2 has an autocatalytic site, which gets...

    Mohd Altaf Najar, D. A. B. Rex… in Journal of Cell Communication and Signaling (2021)

  5. No Access

    Article

    A network map of endothelin mediated signaling pathway

    Shobha Dagamajalu, D.A.B. Rex… in Journal of Cell Communication and Signaling (2021)

  6. No Access

    Article

    Antioxidant Activity and Role of Culture Condition in the Optimization of Red Pigment Production by Talaromyces purpureogenus KKP Through Response Surface Methodology

    The red pigment production by Talaromyces purpureogenus KKP, a soil isolate, was optimized by response surface methodology (RSM) in the present study. The cultural parameters, such as pH, temperature, dextrose, a...

    Kishor Kumar Keekan, Sweta Hallur, Prashant Kumar Modi… in Current Microbiology (2020)

  7. Article

    Open Access

    Aberrant activation of neuronal cell cycle caused by dysregulation of ubiquitin ligase Itch results in neurodegeneration

    It is critical for the neuronal cell cycle to remain suppressed in terminally differentiated neurons as its activation results in aberrant cell cycle re-entry that causes neuronal apoptosis (CRNA), which has b...

    Monika Chauhan, Prashant Kumar Modi, Pushkar Sharma in Cell Death & Disease (2020)

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    Article

    The 5-Hydroxytryptamine signaling map: an overview of serotonin-serotonin receptor mediated signaling network

    The monoamine neurotransmitter, 5-Hydroxytryptamine or serotonin, is derived from tryptophan and synthesized both centrally and systemically. Fourteen structurally and functionally distinct receptor subtypes h...

    Apeksha Sahu, Lathika Gopalakrishnan… in Journal of Cell Communication and Signaling (2018)