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  1. Article

    Open Access

    Whole exome sequencing identifies novel variants of PIK3CA and validation of hotspot mutation by droplet digital PCR in breast cancer among Indian population

    Breast cancer (BC) is the most common malignancy with very high incidence and relatively high mortality in women. The PIK3CA gene plays a pivotal role in the pathogenicity of breast cancer. Despite this, the m...

    Rahul Kumar, Rakesh Kumar, Harsh Goel, Sonu Kumar… in Cancer Cell International (2023)

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  2. No Access

    Article

    Evaluation of high-risk human papillomavirus in sinonasal papillomas and squamous cell carcinomas

    The sinonasal tract is considered a second hotspot for human papillomavirus (HPV)-related tumors in the head and neck, with HPV being identified in up to 62% of squamous cell carcinomas (SCCs) and 38% of papil...

    Aanchal Kakkar, Shraddhanjali Satapathy, Kapil Sikka, Pranay Tanwar… in Virchows Archiv (2023)

  3. Article

    Open Access

    Ubiquitin specific peptidase 37 and PCNA interaction promotes osteosarcoma pathogenesis by modulating replication fork progression

    Osteosarcoma is a type of bone cancer that predominantly affects young individuals, including children and adolescents. The disease progresses through heterogeneous genetic alterations, and patients often deve...

    Ravi Chauhan, Ashna Gupta, Lakshay Malhotra… in Journal of Translational Medicine (2023)

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  4. Article

    Open Access

    Presence of entry receptors and viral markers suggest a low level of placental replication of hepatitis B virus in a proportion of pregnant women infected with chronic hepatitis B

    The transplacental route of vertical transmission of Hepatitis B Virus (HBV) has been known for over a decade. Here we present evidence which suggest HBV can replicate in placenta. Forty-one HBsAg positive and...

    Garima Garg, M. N. Meenu, Kajal Patel, Ravinder Singh, Priyal Gupta… in Scientific Reports (2022)

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  5. No Access

    Article

    Unravelling the molecular mechanism of mutagenic factors impacting human health

    Environmental mutagens are chemical and physical substances in the environment that has a potential to induce a wide range of mutations and generate multiple physiological, biochemical, and genetic modificatio...

    Keshav Goyal, Harsh Goel, Pritika Baranwal… in Environmental Science and Pollution Resear… (2022)

  6. No Access

    Article

    Structural based screening of potential inhibitors of SMAD4: a step towards personalized medicine for gall bladder and other associated cancers

    Gall bladder cancer (GBC) is an aggressive and most common malignancy of biliary tract lacking effective treatment due to unavailability of suitable biomarkers and therapeutics. SMAD4 is an essential mediator ...

    Rakesh Kumar, Rahul Kumar, Pranay Tanwar in Molecular Diversity (2021)

  7. No Access

    Chapter and Conference Paper

    Influence of Process Parameters on Weld Bead Geometry and Mechanical Properties in GTAW

    In this paper, the structural and mechanical properties of IS:2062 mild steel after single-pass gas tungsten arc welding (GTAW) were investigated and evaluated, to reveal the weld strength and microhardness of...

    Radha Kant, Shailendra Pandey, Renu Singh… in Trends in Manufacturing Processes (2020)

  8. No Access

    Article

    Esophageal Squamous Cell Carcinoma Metastatic to Umbilicus: a Case Report with Review of Literature

    Garima Jain, Chandan Kumar, Nishikant Damle… in Journal of Gastrointestinal Cancer (2019)

  9. No Access

    Article

    Real-Time Compensation in Flow Cytometry: A Real Need of Time

    Aroonima Misra, Sunanda Chauhan… in Indian Journal of Hematology and Blood Tra… (2018)