3 Result(s)
within
Pin Ye
Life Sciences
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Article
Open AccessPKCδ regulates the vascular biology in diabetic atherosclerosis
Diabetes mellitus, known for its complications, especially vascular complications, is becoming a globally serious social problem. Atherosclerosis has been recognized as a common vascular complication mechanism...
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Article
Open AccessScorpion toxin BmK I directly activates Nav1.8 in primary sensory neurons to induce neuronal hyperexcitability in rats
Voltage-gated sodium channels (VGSCs) in primary sensory neurons play a key role in transmitting pain signals to the central nervous system. BmK I, a site-3 sodium channel-specific toxin from scorpion Buthus mart...
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Article
Exploring the obscure profiles of pharmacological binding sites on voltage-gated sodium channels by BmK neurotoxins
Diverse subtypes of voltage-gated sodium channels (VGSCs) have been found throughout tissues of the brain, muscles and the heart. Neurotoxins extracted from the venom of the Asian scorpion Buthus martensi Karsch ...
