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Article
Stem cell-derived exosomes for chronic wound repair
Stem cells possess the capability of self-renewal and multipotency, which endows them with great application potential in wound repair fields. Yet, several problems including immune concerns, ethical debates, ...
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Article
Study on fatigue strength of FSW joints of 5083 aluminum alloy with kissing bond defect
This work studied the effect of kissing bond defects on the fatigue strength of friction stir welded (FSW) specimens and assessed fatigue life prediction approaches for the fatigue strength evaluation of frict...
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Article
Metal-organic frameworks nanoswitch: Toward photo-controllable endo/lysosomal rupture and release for enhanced cancer RNA interference
Endo/lysosomal escape and gene release are two critical bottlenecks in gene delivery. Herein, a novel photo-controllable metal-organic frameworks (MOFs) nanoswitch is rationally designed for enhancing small in...
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Article
Open AccessBoron delivery agents for neutron capture therapy of cancer
Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the nuclear capture and fission reactions that occur when the stable isotope, boron-10, is irradiated with neutrons to produc...
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Article
A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy
Engineered nanoparticles that respond to pathophysiological parameters, such as pH or redox potential, have been developed as contrast agents for the magnetic resonance imaging (MRI) of tumours. However, beyon...
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Article
In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent
A more immediate impact for therapeutic approaches of current clinical research efforts is of major interest, which might be obtained by develo** a noninvasive radiation dose-escalation strategy, and neutron...
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Chapter
Polymeric Nanocarriers for Cancer Therapy
In the past decades, polymeric nanocarriers have emerged as a biocompatible platform for delivering therapeutic compounds to tumor sites in a cancer-selective manner, and some polymeric nanocarriers have alrea...