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  1. No Access

    Article

    Responses of bird communities to riparian park habitat factors: a case study in a highly urbanized area of Fuzhou city, China

    Urban riverside parks are important habitats for fall wildlife, but the relationship between birds and habitats in highly urbanized areas is unclear. Our study was to explore relationship with avian species an...

    Dulai Zheng, Peilin Huang, Weizhen Xu… in Environment, Development and Sustainability (2023)

  2. Article

    Open Access

    Spin-related symmetry breaking induced by half-disordered hybridization in BixEr2-xRu2O7 pyrochlores for acidic oxygen evolution

    While acidic oxygen evolution reaction plays a critical role in electrochemical energy conversion devices, the sluggish reaction kinetics and poor stability in acidic electrolyte challenges materials developme...

    Gang Zhou, Peifang Wang, Bin Hu, **nyue Shen, Chongchong Liu… in Nature Communications (2022)

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  3. Article

    Open Access

    Gene expression profiles provide insights into the survival strategies in deep-sea mussel (Bathymodiolus platifrons) of different developmental stages

    Deep-sea mussels living in the cold seeps with enormous biomass act as the primary consumers. They are well adapted to the extreme environment where light is absent, and hydrogen sulfide, methane, and other hy...

    Junrou Huang, Peilin Huang, Jianguo Lu, Nengyou Wu, Genmei Lin, **lin Zhang… in BMC Genomics (2022)

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  4. Article

    Open Access

    Enhancement of scutellarin oral delivery efficacy by vitamin B12-modified amphiphilic chitosan derivatives to treat type II diabetes induced-retinopathy

    Diabetic retinopathy is the most common complication in diabetic patients relates to high expression of VEGF and microaneurysms. Scutellarin (Scu) turned out to be effective against diabetes related vascular e...

    **gnan Wang, Jiayun Tan, Jiahao Luo, Peilin Huang… in Journal of Nanobiotechnology (2017)

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  5. No Access

    Article

    Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway

    Altered cellular metabolism has received increased attention as an important hallmark of cancer. Activation of FASN has been found to be involved in many human tumors. Despite extensive research in FASN funct...

    Ligong Chang, Peng Wu… in Journal of Cancer Research and Clinical On… (2016)

  6. No Access

    Article

    High mixing effectiveness lobed nozzles and mixing mechanisms

    For a circular lobed nozzle with the exit plane displaced from the center body, adding a central plug at exit or replacing the nozzle with an alternating-lobe nozzle can improve the mixing effectiveness. In th...

    ZhiQiang Sheng, ShiChun Chen, Zhe Wu, PeiLin Huang in Science China Technological Sciences (2015)

  7. Article

    Open Access

    Expressions of fatty acid synthase and HER2 are correlated with poor prognosis of ovarian cancer

    The present study was designed to explore the cross talk between fatty acid synthase (FASN) and HER2 (ErbB2) in ovarian cancer. A total of 60 ovarian cancer patients and 15 normal ovarian tissues were enrolled...

    Yunlang Cai, **gmei Wang, Lin Zhang, Di Wu, Dandan Yu, **aoqiang Tian… in Medical Oncology (2014)

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  8. No Access

    Article

    The possible protective mechanism of Hyperbaric oxygen (HBO) in memory impairments induced by Aβ25–35 in rats

    Alzheimer’s disease is characterized by the accumulation and deposition of Aβ peptides in human brains. Aβ peptides are toxic to neurons by lots of mechanisms of which Aβ induced oxidative stress is one of the...

    **aoQiang Tian, LiDa Zhang, **gMei Wang… in Central European Journal of Medicine (2013)

  9. Article

    Open Access

    Loss of fatty acid synthase inhibits the “HER2-PI3K/Akt axis” activity and malignant phenotype of Caco-2 cells

    Fatty acid synthase (FASN) is frequently activated and overexpressed in human cancers, and plays a crucial role in the carcinogenesis of various cancers. In this study, our aims were to explore the role of FAS...

    Nan Li, Heng Lu, Chunyan Chen, **aodong Bu, Peilin Huang in Lipids in Health and Disease (2013)

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  10. No Access

    Article

    The “HER2–PI3K/Akt–FASN Axis” Regulated Malignant Phenotype of Colorectal Cancer Cells

    Recent evidence suggests that HER2 (ErbB2; Her-2/neu) and the related PI3K/Akt signaling pathway substantially affect the malignant phenotype of colorectal cancer cells. Moreover, fatty acid synthase (FASN), w...

    Nan Li, **aodong Bu, Peng Wu, **** Wu, Peilin Huang in Lipids (2012)

  11. No Access

    Article

    Expression of p53, Ki-67 and c-Myc Proteins is Predictive of the Surgical Molecular Margin in Colorectal Carcinoma

    Surgical resection is the mainstay of treatment for colorectal carcinoma, however, the overall survival is modest due to frequent local recurrence from residual cancer cells after “curative” resection. Therefo...

    Nan Li, **gmei Wang, Shanshan Shen, **aodong Bu… in Pathology & Oncology Research (2011)

  12. No Access

    Article

    Molecular detection of disseminated tumor cells in the peripheral blood in patients with gastrointestinal cancer

    In this study, 62 preoperative peripheral blood samples from patients with gastrointestinal carcinomas, 12 healthy volunteers, and ten patients with inflammatory gastrointestinal diseases were analyzed for the...

    Peilin Huang, **gmei Wang, Ying Guo… in Journal of Cancer Research and Clinical On… (2003)