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Article
Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers
Interactions between ticagrelor and atorvastatin or simvastatin were investigated in two-way crossover studies.
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Article
Bronchoscopic Management of Malignant Airway Obstruction
Approximately one-third of patients with lung cancer will develop airway obstruction and many cancers lead to airway obstruction through meta stases. The treatment of malignant airway obstruction is often a mu...
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Article
Open AccessIL-25 and IL-33 induce Type 2 inflammation in basophils from subjects with allergic asthma
The alarmin cytokines IL-25 and IL-33 are key promoters of type 2 inflammation. Basophils respond to alarmin cytokines, however the relationship of these cytokines with basophil activation and recruitment in h...
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Article
Open AccessTherapeutic interventions in severe asthma
The present paper addresses severe asthma which is limited to 5-10% of the overall population of asthmatics. However, it accounts for 50% or more of socials costs of the disease, as it is responsible for hospi...
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Chapter
Anti-IgE and Biologic Approaches for the Treatment of Asthma
Current asthma treatments are effective for the majority of patients with mild-to-moderate disease. However, in those with more severe refractory asthma, agents other than inhaled corticosteroids and beta-agon...
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Article
Open AccessClarifying SABA overuse: Translating Canadian Thoracic Society guidelines into clinical practice
Patients with asthma frequently over rely on short-acting beta-agonists (SABA) to treat acute symptoms. This can adversely impact quality of life and increase the risk of exacerbations. SABA overuse is also as...
