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  1. Article

    Bronchoscopic Management of Malignant Airway Obstruction

    Approximately one-third of patients with lung cancer will develop airway obstruction and many cancers lead to airway obstruction through meta stases. The treatment of malignant airway obstruction is often a mu...

    Patrick D. Mitchell, Marcus P. Kennedy in Advances in Therapy (2014)

  2. Article

    Open Access

    IL-25 and IL-33 induce Type 2 inflammation in basophils from subjects with allergic asthma

    The alarmin cytokines IL-25 and IL-33 are key promoters of type 2 inflammation. Basophils respond to alarmin cytokines, however the relationship of these cytokines with basophil activation and recruitment in h...

    Brittany M. Salter, John Paul Oliveria, Graeme Nusca in Respiratory Research (2016)

  3. Article

    Open Access

    Therapeutic interventions in severe asthma

    The present paper addresses severe asthma which is limited to 5-10% of the overall population of asthmatics. However, it accounts for 50% or more of socials costs of the disease, as it is responsible for hospi...

    Giorgio Walter Canonica, Gianenrico Senna in World Allergy Organization Journal (2016)

  4. Article

    Open Access

    Clarifying SABA overuse: Translating Canadian Thoracic Society guidelines into clinical practice

    Patients with asthma frequently over rely on short-acting beta-agonists (SABA) to treat acute symptoms. This can adversely impact quality of life and increase the risk of exacerbations. SABA overuse is also as...

    Anne K. Ellis, Vanessa Foran, Alan Kaplan in Allergy, Asthma & Clinical Immunology (2022)