8 Result(s)
within
Patrick Corran
English
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Article
Open AccessThe establishment of a WHO Reference Reagent for anti-malaria (Plasmodium falciparum) human serum
At a World Health Organization (WHO) sponsored meeting it was concluded that there is an urgent need for a reference preparation that contains antibodies against malaria antigens in order to support serology s...
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Article
Open AccessSerology describes a profile of declining malaria transmission in Farafenni, The Gambia
Malaria morbidity and mortality has declined in recent years in a number of settings. The ability to describe changes in malaria transmission associated with these declines is important in terms of assessing t...
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Article
Open AccessGenetic determinants of anti-malarial acquired immunity in a large multi-centre study
Many studies report associations between human genetic factors and immunity to malaria but few have been reliably replicated. These studies are usually country-specific, use small sample sizes and are not dir...
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Article
Open AccessGlucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in Dogon and Fulani, Mali
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with protection from severe malaria, and potentially uncomplicated malaria phenotypes. It has been documented that G6PD deficiency in sub-Sahar...
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Open AccessGenetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka
The incidence of malaria in Sri Lanka has significantly declined in recent years. Similar trends were seen in Kataragama, a known malaria endemic location within the southern province of the country, over the ...
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Open AccessFilter paper collection of Plasmodium falciparum mRNA for detecting low-density gametocytes
Accurate sampling of sub-microscopic gametocytes is necessary for epidemiological studies to identify the infectious reservoir of Plasmodium falciparum. Detection of gametocyte mRNA achieves sensitive detection, ...
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Open AccessComparison of surveillance methods applied to a situation of low malaria prevalence at rural sites in The Gambia and Guinea Bissau
Health record-based observations from several parts of Africa indicate a major decline in malaria, but up-to-date information on parasite prevalence in West-Africa is sparse. This study aims to provide parasit...
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Genome-wide and fine-resolution association analysis of malaria in West Africa
Dominic Kwiatkowski and colleagues of the MalariaGEN and the WTCCC consortiums report a genome-wide analysis of severe malaria in The Gambia. They provide guidance for design of GWAS in African populations, an...
