6 Result(s)
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Lotus L. van den Hoogen
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Article
Open AccessSARS-CoV-2 Spike S1-specific IgG kinetic profiles following mRNA or vector-based vaccination in the general Dutch population show distinct kinetics
mRNA- and vector-based vaccines are used at a large scale to prevent COVID-19. We compared Spike S1-specific (S1) IgG antibodies after vaccination with mRNA-based (Comirnaty, Spikevax) or vector-based (Janssen...
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Article
Open AccessConsiderations for quality assurance of multiplex malaria antigen detection assays with large sample sets
Multiplex assays for malaria antigen detection can gather data from large sample sets, but considerations for the consistency and quality assurance (QA) of mass testing lack evaluation. We present a QA framewo...
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Article
Open AccessProgrammatic options for monitoring malaria in elimination settings: easy access group surveys to investigate Plasmodium falciparum epidemiology in two regions with differing endemicity in Haiti
As in most eliminating countries, malaria transmission is highly focal in Haiti. More granular information, including identifying asymptomatic infections, is needed to inform programmatic efforts, monitor inte...
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Open AccessQuality control of multiplex antibody detection in samples from large-scale surveys: the example of malaria in Haiti
Measuring antimalarial antibodies can estimate transmission in a population. To compare outputs, standardized laboratory testing is required. Here we describe the in-country establishment and quality control (...
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Open AccessComparison of diagnostics for the detection of asymptomatic Plasmodium falciparum infections to inform control and elimination strategies
The global burden of malaria has been substantially reduced over the past two decades. Future efforts to reduce malaria further will require moving beyond the treatment of clinical infections to targeting mala...
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Article
Open AccessSerology describes a profile of declining malaria transmission in Farafenni, The Gambia
Malaria morbidity and mortality has declined in recent years in a number of settings. The ability to describe changes in malaria transmission associated with these declines is important in terms of assessing t...
