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  1. Article

    Open Access

    Standardization of molecular monitoring of CML: results and recommendations from the European treatment and outcome study

    Standardized monitoring of BCR::ABL1 mRNA levels is essential for the management of chronic myeloid leukemia (CML) patients. From 2016 to 2021 the European Treatment and Outcome Study for CML (EUTOS) explored the...

    Helen E. White, Matthew Salmon, Francesco Albano, Christina Søs Auður Andersen… in Leukemia (2022)

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  2. Article

    Open Access

    Impact of BCR::ABL1 transcript type on RT-qPCR amplification performance and molecular response to therapy

    Several studies have reported that chronic myeloid leukaemia (CML) patients expressing e14a2 BCR::ABL1 have a faster molecular response to therapy compared to patients expressing e13a2. To explore the reason for ...

    Matthew Salmon, Helen E. White, Hana Zizkova, Andrea Gottschalk, Eliska Motlova… in Leukemia (2022)

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  3. Article

    Open Access

    Diagnostic methods and therapeutic options of uveal melanoma with emphasis on MR imaging—Part II: treatment indications and complications

    Therapy of uveal melanoma aims to preserve the eye and its function and to avoid metastatic dissemination. The treatment choice is difficult and must keep into account several factors; the therapeutic strategy...

    Pietro Valerio Foti, Mario Travali, Renato Farina… in Insights into Imaging (2021)

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  4. Article

    Open Access

    Diagnostic methods and therapeutic options of uveal melanoma with emphasis on MR imaging—Part I: MR imaging with pathologic correlation and technical considerations

    Uveal melanoma is a malignant neoplasm that derives from pigmented melanocytes of the uvea and involves, in order of decreasing prevalence, the choroid, ciliary body and iris. Its prognosis is related to histo...

    Pietro Valerio Foti, Mario Travali, Renato Farina… in Insights into Imaging (2021)

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  5. No Access

    Chapter

    Biomarkers

    In the era of personalized medicine, biomarkers represent an irreplaceable tool for cancer screening, diagnosis, and management. As molecular biology techniques rapidly improve, several potential biomarkers ha...

    Fiorella Guadagni, Sofia Cutaia, Giorgio Madonia… in Practical Medical Oncology Textbook (2021)

  6. No Access

    Article

    Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to Hepatocyte Growth Factor

    The Hepatocyte Growth Factor (HGF) and its receptor Met are physiological regulators of cell migration. HGF and Met have also been implicated in tumor progression and metastasis. We show here that the tyrosine...

    Francesco Frasca, Paolo Vigneri, Veronica Vella, Riccardo Vigneri… in Oncogene (2001)