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Open AccessThe Results of the URRAH (Uric Acid Right for Heart Health) Project: A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation
The relationship between Serum Uric Acid (UA) and Cardiovascular (CV) diseases has already been extensively evaluated, and it was found to be an independent predictor of all-cause and cardiovascular mortality ...
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Open AccessExaggerated blood pressure response to standing in young-to-middle-age subjects: prevalence and factors involved
To investigate the prevalence of orthostatic hypertension and the association of the blood pressure (BP) level, supine BP decline, and white-coat effect with the orthostatic pressor response.
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High Heart Rate: A Predictor of Heart Failure in Healthy Subjects and a Risk Factor for Adverse Outcome in Patients with Heart Failure
Heart failure (HF) is characterized by neurohumoral activation of the sympathetic nervous system, which is accompanied by increased heart rate (HR), myocardial contractility, and vascular tone. The compensator...
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Identification of a plausible serum uric acid cut-off value as prognostic marker of stroke: the Uric Acid Right for Heart Health (URRAH) study
The Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension conceived and designed an ad hoc study aimed at searching for prognostic cut-off values of serum uric acid (SUA) in...
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Correction to: Carotid elasticity is impaired in stage 1 hypertensive patients with well-controlled blood pressure levels
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Carotid elasticity is impaired in stage 1 hypertensive patients with well-controlled blood pressure levels
Whether impaired arterial elasticity in stage 1 hypertension can be brought back to normal by antihypertensive treatment is unknown. Aim of this study was to evaluate the impact of long-term well-controlled bl...
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Effects of Physical Activity on Hypertension of Youth
Sedentary habits leading to obesity and metabolic disturbances are responsible for the rise in the prevalence of hypertension among adolescents and young individuals. Regular aerobic exercise has been shown to...
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Open AccessAssociation of uric acid with kidney function and albuminuria: the Uric Acid Right for heArt Health (URRAH) Project
Hyperuricemia is commonly observed in patients with chronic kidney disease (CKD). However, a better understanding of the relationship among uric acid (UA) values, glomerular filtration rate (GFR) and albuminur...
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Haemodynamics of Exercise Testing and Sports Activities
Haemodynamic changes caused by exercise in human beings have been studied almost exclusively during laboratory tests. However, blood pressure (BP) recordings performed “in the field” have shown that the BP beh...
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Open AccessThe importance of including uric acid in the definition of metabolic syndrome when assessing the mortality risk
Serum uric acid (SUA) has been depicted as a contributory causal factor in metabolic syndrome (MS), which in turn, portends unfavourable prognosis.
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Augmentation index predicts mortality in patients with aortic stenosis: an echo-tracking study
Aortic valve stenosis (AS) shares similarities with the atherosclerotic process but little is known about the effect of the mechanical properties of large arteries on outcome in patients with AS. The aims of t...
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In search of the optimal cuff for blood pressure measurement in people with severe obesity
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Cuff Design for Home Blood Pressure Monitors
Devices for home blood pressure (BP) measurement must be provided with cuffs that have optimal size and shape in relation to the patient’s arm. However, optimal characteristics of cuffs for BP measurement are ...
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Devices for Home Blood Pressure Monitoring
While home blood pressure (BP) monitoring (HBPM) for hypertension management is recommended by recent guidelines, very few recommendations are provided on the proper choices for devices. In the absence of guid...
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Impact of Exercise on Cardiovascular Risk Factors: Arterial Hypertension
Hypertension is defined as a systolic blood pressure (BP) ≥ 140 mmHg and/or diastolic BP ≥ 90 mmHg or being on antihypertensive treatment. BP in excess of 140/90 mmHg is further categorized in terms of severit...
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Tachycardia in Prehypertension
Prehypertension is a heterogeneous condition, and the cardiovascular risk differs in relation to many clinical variables, such as age, blood pressure level, and associated risk factors. Among these, resting he...
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Arterial Distensibility, Physical Activity, and the Metabolic Syndrome
Metabolic syndrome (MetS), a cluster of risk factors including central obesity, metabolic abnormalities, and arterial hypertension, is a well-known determinant of arterial wall remodeling and stiffening. The m...
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Low night-time heart rate is longitudinally associated with lower augmentation index and central systolic blood pressure in hypertension
Several studies have shown that the augmentation index (AIx) is negatively correlated with heart rate (HR). This led some authors to claim that the use of HR-lowering drugs may be detrimental in hypertension. ...
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Isolated Systolic Hypertension in Young Individuals: Pathophysiological Mechanisms, Prognostic Significance, and Clinical Implications
Isolated systolic hypertension (ISH) is the most common form of hypertension in older persons and its predictive value for adverse outcome is well known. However, ISH can be frequently found also in young indi...
