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Living Reference Work Entry In depth
Detecting Active Molecular Subpathways Related to Alzheimer’s Disease: A Systems Biology Approach
Pathway analysis is a thriving research area of Systems Biology tools and methodologies which aim to unravel the inherent complexity of high-throughput biological data produced by the advent of Omics technolog...
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Article
Mathematical Multidimensional Modelling and Structural Artificial Intelligence Pipelines Provide Insights for the Designing of Highly Specific AntiSARS-CoV2 Agents
COVID19 is the most impactful pandemic of recent times worldwide. It is a highly infectious disease that is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 virus), To date there is specif...
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Chapter and Conference Paper
Correction to: Development of a Protein Biochip Platform for Parkinson’s Disease
In the original version of this chapter, the acknowledgment section was not provided by the author. The acknowledgment has been updated now in this revised version of the chapter as mentioned below:
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Chapter and Conference Paper
Mobile Application for Monitoring and Preventing Cognitive Decline Through Lifestyle Intervention
Diagnosing and preventing Alzheimer’s disease is a complex task, partly due to being characterized by a lengthy asymptomatic stage. In order to tackle this, most preclinical studies are multidimensional in nat...
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Chapter and Conference Paper
Bioinformatics Approaches for Parkinson’s Disease in Clinical Practice: Data-Driven Biomarkers and Pharmacological Treatment
Parkinson’s disease is a gradually progressive neurodegenerative disorder characterized by a selective loss of dopaminergic neurons in the midbrain area called the substantia nigra pars compacta and cytoplasmi...
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Chapter and Conference Paper
The Importance of Diagnostic and Prognostic Biomarker Identification and Classification Towards Understanding ALS Pathogenesis
ALS is increasingly perceived as a multisystem neurodegenerative disorder, and the identification of a panel of biomarkers that accurately reflect features of pathology is a priority, not only for diagnostic p...
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Chapter and Conference Paper
Development of a Protein Biochip Platform for Parkinson’s Disease
Parkinson’s disease (PD) is a complex neurodegenerative disorder, characterized by severe motor symptoms which lead to progressive weakness of motor function caused by prominent loss of dopamine-secreting neur...
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Chapter and Conference Paper
Genetic Pathways Involved in the Pathogenesis of Parkinson’s Disease
Parkinson’s disease (PD) is the second most common neurodegenerative disease. PD pathogenesis includes both genetic and environmental factors. Previous studies have linked the disease with several genes such a...
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Living Reference Work Entry In depth
Gene Expression Profiling and Bioinformatics Analysis in Neurodegenerative Diseases
The integration of experimental and clinical information is important for understanding complex biological systems and addressing medical issues. Gene expression profiling affords the opportunity to explore th...
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Living Reference Work Entry In depth
Biomedical Applications of Precision Medicine in Neurodegenerative Diseases
Healthcare has seen massive data growth over the last several years, with some reports estimating that healthcare data generation increases by 48% annually. The advent of personalized and precision medicine de...
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Book and Living Reference Work (Continuously updated edition)
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Chapter and Conference Paper
Correction to: GeNeDis 2018: Computational Biology and Bioinformatics
In the original version of this book, Chapter 20 was inadvertently published without carrying the corrections provided by the author. This has now been rectified in this revised version of the book.
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Chapter and Conference Paper
Alzheimer’s Disease: The Role of Mutations in Protein Folding
Misfolded proteins result when a protein follows the wrong folding pathway. Accumulation of misfolded proteins can cause disorders, known as amyloid diseases. Unfortunately, some of them are very common. The m...
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Chapter and Conference Paper
Modeling the Critical Activation of Chaperone Machinery in Protein Folding
Protein homeostasis is a dynamic network that plays a pivotal role in systems’ maintenance within a cell. This quality control system involves a number of mechanisms regarding the process of protein folding. C...
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Chapter and Conference Paper
Exhaled Breath Condensate (EBC): Is It a Viable Source of Biomarkers for Lung Diseases?
The exhaled breath condensate is a source of biomarkers with many advantages and benefits compared to other traditional sampling techniques in respiratory medicine. It is a biological product that is formed by...
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Chapter and Conference Paper
Amyotrophic Lateral Sclerosis: Current Status in Diagnostic Biomarkers
Amyotrophic lateral sclerosis (ALS) is a rare, neurodegenerative disease that affects the human motor system. ALS is a highly heterogeneous disease, depending on several causative factors. The heterogeneity of...
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Chapter and Conference Paper
A Systems Biology Approach for the Identification of Active Molecular Pathways During the Progression of Alzheimer’s Disease
In the last years, systems-level network-based approaches have gained ground in the research field of systems biology. These approaches are based on the analysis of high-throughput sequencing studies, which ar...
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Chapter and Conference Paper
Buccal Mucosa Biomarkers in Alzheimer’s Disease
Alzheimer’s disease (AD) precipitation in the elderly population increases the need for sensitive biomarkers that can be applied to large population screening. Buccal cells can be obtained easily, noninvasivel...
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Chapter and Conference Paper
Undergraduate Students’ Brain Activity in Visual and Textual Programming
Eight computer science students, novice programmers, who were in the first semester of their studies, participated in a field study in order to explore potential differences in their brain activity during prog...
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Chapter and Conference Paper
A Hypothesis of Circulating MicroRNAs’ Implication in High Incidence of Atrial Fibrillation and Other Electrocardiographic Abnormalities in Cancer Patients
MicroRNAs are short non-coding RNA molecules that control posttranscriptional gene expression and are present in tissues cells but also circulate in biological fluids in various forms (exosome, connected with ...
