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  1. No Access

    Reference Work Entry In depth

    Biomedical Applications of Precision Medicine in Neurodegenerative Diseases

    Healthcare has seen massive data growth over the last several years, with some reports estimating that healthcare data generation increases by 48% annually. The advent of personalized and precision medicine de...

    Eleftheria Polychronidou, Panagiotis Vlamos in Handbook of Computational Neurodegeneration (2023)

  2. Article

    Open Access

    RiskRadar: development and pilot results of a technical intervention targeting combination prevention regarding HIV, viral hepatitis, sexually transmitted infections and tuberculosis

    The HIV pandemic impacts the lives of millions and despite the global coordinated response, innovative actions are still needed to end it. A major challenge is the added burden of coinfections such as viral he...

    Christine Kakalou, Eleftheria Polychronidou, Vicky Drosou… in BMC Infectious Diseases (2021)

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  3. No Access

    Living Reference Work Entry In depth

    Biomedical Applications of Precision Medicine in Neurodegenerative Diseases

    Healthcare has seen massive data growth over the last several years, with some reports estimating that healthcare data generation increases by 48% annually. The advent of personalized and precision medicine de...

    Eleftheria Polychronidou, Panayiotis Vlamos in Handbook of Computational Neurodegeneration

  4. No Access

    Chapter and Conference Paper

    Alzheimer’s Disease: The Role of Mutations in Protein Folding

    Misfolded proteins result when a protein follows the wrong folding pathway. Accumulation of misfolded proteins can cause disorders, known as amyloid diseases. Unfortunately, some of them are very common. The m...

    Eleftheria Polychronidou, Antigoni Avramouli, Panayiotis Vlamos in GeNeDis 2018 (2020)

  5. Article

    Open Access

    Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia

    Although the etiology of chronic lymphocytic leukemia (CLL), the most common type of adult leukemia, is still unclear, strong evidence implicates antigen involvement in disease ontogeny and evolution. Primary ...

    Eleftheria Polychronidou, Ilias Kalamaras, Andreas Agathangelidis… in BMC Bioinformatics (2018)

    Download PDF (1696 KB) View Article

  6. No Access

    Chapter and Conference Paper

    Parkinson’s Disease Patients Classification Based on a Motion Tracking Methodology

    This study demonstrates how a computer based methodology for tracking motor abilities of Parkinson’s disease can be utilized for patient classification and assessment of the Parkinson’s disease severity. The L...

    Eleftheria Polychronidou, Sofia Segkouli… in Precision Medicine Powered by pHealth and … (2018)

  7. No Access

    Chapter and Conference Paper

    Chronic Lymphocytic Leukemia Patient Clustering Based on Somatic Hypermutation (SHM) Analysis

    Somatic Hypermutation (SHM) load in the immunoglobulin heavy variable (IGHV) gene of the clonotypic B cell receptor immunoglobulin (BcR IG) is one of the most important prognostic markers in CLL, segregating p...

    Eleftheria Polychronidou, Aliki Xochelli, Panagiotis Moschonas… in GeNeDis 2016 (2017)

  8. No Access

    Chapter and Conference Paper

    3D Protein-Structure-Oriented Discovery of Clinical Relation Across Chronic Lymphocytic Leukemia Patients

    Chronic lymphocytic leukemia (CLL) is the most common adult leukemia with still unclear etiology. Indications of antigenic pressure have been hinted, using sequence and structure-based reasoning. The accuracy...

    Konstantinos Mochament, Andreas Agathangelidis… in Bioinformatics and Biomedical Engineering (2017)

  9. No Access

    Chapter and Conference Paper

    Notch Signaling and Ageing

    Notch signaling is a master controller of the neural stem cell and neural development maintaining a significant role in the normal brain function. Notch genes are involved in embryogenesis, nervous system, and...

    Eleftheria Polychronidou, Dimitrios Vlachakis, Panayiotis Vlamos… in GeNeDis 2014 (2015)