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Article
Open AccessCYP2C8 and CYP2C9 polymorphisms in relation to tumour characteristics and early breast cancer related events among 652 breast cancer patients
CYP2C8/9 polymorphisms may influence breast cancer-free survival after diagnosis due to their role in the metabolism of tamoxifen, paclitaxel, and other chemotherapy. cytochrome P450 (CYP)2C8/9 metabolise arachid...
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Article
Proliferation of the breast epithelium in relation to menstrual cycle phase, hormonal use, and reproductive factors
The proliferative rate in normal breast epithelium from 58 women undergoing reduction mammoplastics was studied using the formalin resistant antibody Ki-S5, and related to age at operation, menstrual cycle pha...
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Article
Incorporation of 5-fluorouracil into rat liver tumor and normal tissues and the liver nucleotide profile after administration by the hepatic artery during portal venous branch ligation
A therapeutic dose of labelled 5-fluorouracil (5-FU) was infused via the hepatic artery during 30 min with or without ligation of the left portal venous branch in Wistar rats with a secondary liver cancer in t...
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Article
The incorporation of 5-fluorouracil into rat liver tumor and normal tissues after administration by the hepatic artery during temporary portal vein clam**
A therapeutic dose of labelled 5-fluorouracil (5-FU) was infused via the hepatic artery during 30 min with or without a simultaneous temporary clam** of the portal vein in a model of secondary liver cancer i...
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Article
Hepatic artery administration of degradable starch microspheres
Effects of degradable starch microspheres administered via the hepatic artery were examined in rats in which an adenocarcinoma was transplanted into the liver.3H-uridine or3H-uracil with cold uridine and uracil, ...
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Chapter and Conference Paper
Validity Studies of Some Variables Used in Cancer Epidemiology
Written or oral questionnaires are often used when risk factors are studied in relation to cancer. However the validity of the answers to different questions are more seldom studied although such studies have ...
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Chapter
Tourniquet Infusion with DTIC in Therapy-Resistant Melanoma on the Extremities: A Pilot Study
For three decades regional chemotherapy has been given by intra-arterial infusion or isolated perfusion techniques (Creech et al. 1958; Klopp et al. 1950). The isolation perfusion technique was altered to incl...
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Chapter
Results of Regional Hyperthermic Perfusion for Primary and Recurrent Melanomas of the Extremities
The technique for regional isolated perfusion has remained essentially the same since it was introduced in 1957, with the exception that heat was added in 1967 (Creech et al. 1958; Stehlin 1969). The anticance...