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    Article

    The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus

    The major histocompatibility complex (MHC) class II transactivator gene (CIITA) encodes an important transcription factor required for human leukocyte antigens (HLA) class II MHC-restricted antigen presentation.

    P G Bronson, B A Goldstein, P P Ramsay, K B Beckman, J A Noble in Genes & Immunity (2011)

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    CIITA is not associated with risk of develo** rheumatoid arthritis

    The major histocompatibility complex (MHC) class II transactivator gene (CIITA) encodes an important transcription factor regulating genes required for human leukocyte antigen (HLA) class II MHC-restricted antige...

    P G Bronson, P P Ramsay, M F Seldin, P K Gregersen, L A Criswell in Genes & Immunity (2011)

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    Article

    A candidate gene study of CLEC16A does not provide evidence of association with risk for anti-CCP-positive rheumatoid arthritis

    CLEC16A, a putative immunoreceptor, was recently established as a susceptibility locus for type I diabetes and multiple sclerosis. Subsequently, associations between CLEC16A and rheumatoid arthritis (RA), Addison...

    P G Bronson, P P Ramsay, M F Seldin, P K Gregersen, L A Criswell in Genes & Immunity (2010)

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    Supervised machine learning and logistic regression identifies novel epistatic risk factors with PTPN22 for rheumatoid arthritis

    Investigating genetic interactions (epistasis) has proven difficult despite the recent advances of both laboratory methods and statistical developments. With no ‘best’ statistical approach available, combining...

    F B S Briggs, P P Ramsay, E Madden, J M Norris, V M Holers, T R Mikuls in Genes & Immunity (2010)

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    Article

    Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis

    Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system with a strong genetic component. Variation in the major histocompatibility complex on chromosome 6p21, specifically the HLA...

    L F Barcellos, P P Ramsay, S J Caillier, S Sawcer, J Haines, S Schmidt in Genes & Immunity (2008)