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  1. Article

    Open Access

    Effects of thienopyridine class antiplatelets on bleeding outcomes following robot-assisted radical prostatectomy

    This study aimed to assess the effects of thienopyridine-class antiplatelet agents (including ticlopidine, clopidogrel, and prasugrel) on bleeding complications in patients who underwent robot-assisted radical...

    Masashi Kubota, Mutsushi Kawakita, Satomi Yoshida, Hiroko Kimura in Scientific Reports (2024)

  2. Article

    Open Access

    Tumor immune microenvironment and clinical outcomes in stage IV urothelial cancer: YODO study

    Bladder cancer is the 10th most common cancer globally, with a growing incidence in Japan. Evaluation of molecular, genetic, and cellular biomarkers that predict treatment response and prognosis in patients wi...

    Hiroyuki Nishiyama, Toyonori Tsuzuki in International Journal of Clinical Oncology (2023)

  3. Article

    Open Access

    Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study

    Cross-sectional relationships between nocturia and sleep problems have been well evaluated but the risk association for each incidence is scarcely reported. This analysis included 8076 participants of the Naga...

    Hiromitsu Negoro, Kazuya Setoh, Arinobu Fukunaga, Takahisa Kawaguchi in Scientific Reports (2023)

  4. No Access

    Article

    Reclassification prediction of first-year protocol biopsy on active surveillance of prostate cancer by p2PSA-related parameters: from PRIAS-JAPAN

    There is no useful predictive marker for reclassification on active surveillance. Thus, we aimed to investigate thresholds of [−2] proPSA (p2PSA)-related parameters to predict reclassification of the first-yea...

    Takuma Kato, Hiromi Hirama, Koji Mitsuzuka in Prostate Cancer and Prostatic Diseases (2022)

  5. No Access

    Article

    Prognostic significance of pathogenic variants in BRCA1, BRCA2, ATM and PALB2 genes in men undergoing hormonal therapy for advanced prostate cancer

    The prognostic significance of germline variants in homologous recombination repair genes in advanced prostate cancer (PCa), especially with regard to hormonal therapy, remains controversial.

    Hiroko Kimura, Kei Mizuno, Masaki Shiota, Shintaro Narita in British Journal of Cancer (2022)

  6. Article

    Open Access

    Health-related quality of life with enzalutamide versus flutamide in castration-resistant prostate cancer from the AFTERCAB study

    Patient-reported outcome (PRO) measures can provide valuable information in evaluating patients’ health-related quality of life (HRQoL). Post hoc analysis of the AFTERCAB study was conducted to evaluate the HR...

    Hiroji Uemura, Kazuki Kobayashi in International Journal of Clinical Oncology (2022)

  7. Article

    Open Access

    Author Correction: Comprehensive genomics in androgen receptor-dependent castration-resistant prostate cancer identifies an adaptation pathway mediated by opioid receptor kappa 1

    Yuki Makino, Yuki Kamiyama, J. B. Brown, Toshiya Tanaka in Communications Biology (2022)

  8. Article

    Open Access

    Clinical characteristics of renal transplant recipients who developed de novo donor-specific antigen in Kyoto University Hospital: a case series

    The clinical significance of de novo donor-specific antigen (DSA) in renal transplant recipients is not yet fully understood. This study aimed to report the prevalence of de novo DSA detected in antihuman leuk...

    Kenji Nakamura, Atsuro Sawada, Yuki Kita, ** Kono in Renal Replacement Therapy (2022)

  9. Article

    Open Access

    Comprehensive genomics in androgen receptor-dependent castration-resistant prostate cancer identifies an adaptation pathway mediated by opioid receptor kappa 1

    Castration resistance is a lethal form of treatment failure of prostate cancer (PCa) and is associated with ligand-independent activation of the androgen receptor (AR). It is only partially understood how the ...

    Yuki Makino, Yuki Kamiyama, J. B. Brown, Toshiya Tanaka in Communications Biology (2022)

  10. No Access

    Article

    Pre-pembrolizumab neutrophil-to-lymphocyte ratio (NLR) predicts the efficacy of second-line pembrolizumab treatment in urothelial cancer regardless of the pre-chemo NLR

    Neutrophil-to-lymphocyte ratio (NLR) was reported to be associated with prognosis of urothelial cancer (UC) patients receiving systemic chemotherapy or immunotherapy. However, it has not been elucidated how pr...

    Takashi Kobayashi, Katsuhiro Ito, Takahiro Kojima in Cancer Immunology, Immunotherapy (2022)

  11. No Access

    Chapter and Conference Paper

    Position and Orientation Registration of Intra-abdominal Point Cloud Generated from Stereo Endoscopic Images and Organ 3D Model Using Open3D

    In endoscopic surgery, it is important to search for organs, tumors and blood vessels, recognize their locations, and perform the surgery safely and quickly. Robot-assisted surgery has made it possible to perf...

    Masanao Koeda, Naoya Maeda, Akihiro Hamada in Human-Computer Interaction. Technological … (2022)

  12. No Access

    Article

    Long-term safety of high-dose whole pelvic IMRT for high-risk localized prostate cancer through 10-year follow-up

    The aim of this study was to evaluate the long-term efficacy and safety of whole pelvic intensity-modulated radiation therapy with a simultaneous-integrated boost (WP-SIB-IMRT) for locally advanced prostate ca...

    Rihito Aizawa, Kiyonao Nakamura in International Journal of Clinical Oncology (2021)

  13. No Access

    Article

    The association between missense polymorphisms in SRD5A2 and HSD3B1 and treatment failure with abiraterone for castration-resistant prostate cancer

    Missense polymorphism in HSD3B1, encoding 3β-hydroxysteroid dehydrogenase-1, was associated with outcome after abiraterone treatment. Other androgen-metabolizing enzymes may be involved in therapeutic effect in a...

    Masaki Shiota, Shusuke Akamatsu, Shintaro Narita in The Pharmacogenomics Journal (2021)

  14. Article

    Open Access

    Protocol for development and validation of a prediction model for 5-year risk of incident overactive bladder in the general population: the Nagahama study

    An accurate prediction model could identify high-risk subjects of incident Overactive bladder (OAB) among the general population and enable early prevention which may save on the related medical costs. However...

    Satoshi Funada, Yan Luo, Takashi Yoshioka, Kazuya Setoh, Yasuharu Tabara in BMC Urology (2021)

  15. No Access

    Article

    Recurrent hyperglycemic hyperosmolar state after re-administration of dose-reduced ceritinib, an anaplastic lymphoma kinase inhibitor

    Ceritinib is a second-generation anaplastic lymphoma kinase (ALK) inhibitor with clinical activity in crizotinib-resistant ALK-positive non-small cell lung cancer and in treatment-naïve ALK-positive disease. H...

    Yuka Miyoshi, Osamu Ogawa, Ai Nishida, Masahiro Masuzawa in Diabetology International (2021)

  16. No Access

    Chapter and Conference Paper

    VR-Based Surgery Navigation System with 3D User Interface for Robot-Assisted Laparoscopic Partial Nephrectomy

    We have been develo** a surgical support system for Robot-Assisted Laparoscopic Partial Nephrectomy (RAPN) using augmented reality (AR) technology since April 2014. In our system, three-dimensional computer ...

    Masanao Koeda, Akihiro Hamada, Atsuro Sawada in Human-Computer Interaction. Interaction Te… (2021)

  17. Article

    Retraction Note: In Vitro Transfection of Plasmid DNA by Amine Derivatives of Gelatin Accompanied with Ultrasound Irradiation

    The Editor-in-Chief has retracted this article [1] at the request of the corresponding author. Figure 1B appears to be identical to Figure 1D, despite being under different experimental conditions

    Hossein Hosseinkhani, Teruyoshi Aoyana, Shingo Yamamoto in Pharmaceutical Research (2020)

  18. Article

    Open Access

    Cognitive behavioral therapy for overactive bladder in women: study protocol for a randomized controlled trial

    Overactive bladder (OAB) symptoms affect daily life by decreasing health-related quality of life (HRQol). However, there remain no very effective treatment for OAB. Pharmacotherapy is one of the best treatment...

    Satoshi Funada, Norio Watanabe, Takayuki Goto, Hiromitsu Negoro in BMC Urology (2020)

  19. No Access

    Article

    A comparison of laparoendoscopic single-site surgery versus conventional procedures for laparoscopic donor nephrectomy: a Japanese multi-institutional retrospective study

    Laparoendoscopic single-site donor nephrectomy (LESSDN) is a feasible and effective procedure because of its non-invasiveness and better cosmetic outcomes. However, there have been few multi-institutional stud...

    Takamitsu Inoue, Masayoshi Miura, Masaaki Yanishi, Junya Furukawa in Surgical Endoscopy (2020)

  20. No Access

    Article

    Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

    The overwhelming majority of participants in current genetic studies are of European ancestry. To elucidate disease biology in the East Asian population, we conducted a genome-wide association study (GWAS) wit...

    Kazuyoshi Ishigaki, Masato Akiyama, Masahiro Kanai, Atsushi Takahashi in Nature Genetics (2020)

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