122 Result(s)
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Article
Open AccessEffects of thienopyridine class antiplatelets on bleeding outcomes following robot-assisted radical prostatectomy
This study aimed to assess the effects of thienopyridine-class antiplatelet agents (including ticlopidine, clopidogrel, and prasugrel) on bleeding complications in patients who underwent robot-assisted radical...
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Article
Open AccessTumor immune microenvironment and clinical outcomes in stage IV urothelial cancer: YODO study
Bladder cancer is the 10th most common cancer globally, with a growing incidence in Japan. Evaluation of molecular, genetic, and cellular biomarkers that predict treatment response and prognosis in patients wi...
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Article
Open AccessRisk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study
Cross-sectional relationships between nocturia and sleep problems have been well evaluated but the risk association for each incidence is scarcely reported. This analysis included 8076 participants of the Naga...
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Article
Reclassification prediction of first-year protocol biopsy on active surveillance of prostate cancer by p2PSA-related parameters: from PRIAS-JAPAN
There is no useful predictive marker for reclassification on active surveillance. Thus, we aimed to investigate thresholds of [−2] proPSA (p2PSA)-related parameters to predict reclassification of the first-yea...
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Article
Prognostic significance of pathogenic variants in BRCA1, BRCA2, ATM and PALB2 genes in men undergoing hormonal therapy for advanced prostate cancer
The prognostic significance of germline variants in homologous recombination repair genes in advanced prostate cancer (PCa), especially with regard to hormonal therapy, remains controversial.
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Article
Open AccessHealth-related quality of life with enzalutamide versus flutamide in castration-resistant prostate cancer from the AFTERCAB study
Patient-reported outcome (PRO) measures can provide valuable information in evaluating patients’ health-related quality of life (HRQoL). Post hoc analysis of the AFTERCAB study was conducted to evaluate the HR...
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Article
Open AccessAuthor Correction: Comprehensive genomics in androgen receptor-dependent castration-resistant prostate cancer identifies an adaptation pathway mediated by opioid receptor kappa 1
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Article
Open AccessClinical characteristics of renal transplant recipients who developed de novo donor-specific antigen in Kyoto University Hospital: a case series
The clinical significance of de novo donor-specific antigen (DSA) in renal transplant recipients is not yet fully understood. This study aimed to report the prevalence of de novo DSA detected in antihuman leuk...
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Article
Open AccessComprehensive genomics in androgen receptor-dependent castration-resistant prostate cancer identifies an adaptation pathway mediated by opioid receptor kappa 1
Castration resistance is a lethal form of treatment failure of prostate cancer (PCa) and is associated with ligand-independent activation of the androgen receptor (AR). It is only partially understood how the ...
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Article
Pre-pembrolizumab neutrophil-to-lymphocyte ratio (NLR) predicts the efficacy of second-line pembrolizumab treatment in urothelial cancer regardless of the pre-chemo NLR
Neutrophil-to-lymphocyte ratio (NLR) was reported to be associated with prognosis of urothelial cancer (UC) patients receiving systemic chemotherapy or immunotherapy. However, it has not been elucidated how pr...
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Chapter and Conference Paper
Position and Orientation Registration of Intra-abdominal Point Cloud Generated from Stereo Endoscopic Images and Organ 3D Model Using Open3D
In endoscopic surgery, it is important to search for organs, tumors and blood vessels, recognize their locations, and perform the surgery safely and quickly. Robot-assisted surgery has made it possible to perf...
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Article
Long-term safety of high-dose whole pelvic IMRT for high-risk localized prostate cancer through 10-year follow-up
The aim of this study was to evaluate the long-term efficacy and safety of whole pelvic intensity-modulated radiation therapy with a simultaneous-integrated boost (WP-SIB-IMRT) for locally advanced prostate ca...
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Article
The association between missense polymorphisms in SRD5A2 and HSD3B1 and treatment failure with abiraterone for castration-resistant prostate cancer
Missense polymorphism in HSD3B1, encoding 3β-hydroxysteroid dehydrogenase-1, was associated with outcome after abiraterone treatment. Other androgen-metabolizing enzymes may be involved in therapeutic effect in a...
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Article
Open AccessProtocol for development and validation of a prediction model for 5-year risk of incident overactive bladder in the general population: the Nagahama study
An accurate prediction model could identify high-risk subjects of incident Overactive bladder (OAB) among the general population and enable early prevention which may save on the related medical costs. However...
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Article
Recurrent hyperglycemic hyperosmolar state after re-administration of dose-reduced ceritinib, an anaplastic lymphoma kinase inhibitor
Ceritinib is a second-generation anaplastic lymphoma kinase (ALK) inhibitor with clinical activity in crizotinib-resistant ALK-positive non-small cell lung cancer and in treatment-naïve ALK-positive disease. H...
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Chapter and Conference Paper
VR-Based Surgery Navigation System with 3D User Interface for Robot-Assisted Laparoscopic Partial Nephrectomy
We have been develo** a surgical support system for Robot-Assisted Laparoscopic Partial Nephrectomy (RAPN) using augmented reality (AR) technology since April 2014. In our system, three-dimensional computer ...
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Article
Retraction Note: In Vitro Transfection of Plasmid DNA by Amine Derivatives of Gelatin Accompanied with Ultrasound Irradiation
The Editor-in-Chief has retracted this article [1] at the request of the corresponding author. Figure 1B appears to be identical to Figure 1D, despite being under different experimental conditions
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Article
Open AccessCognitive behavioral therapy for overactive bladder in women: study protocol for a randomized controlled trial
Overactive bladder (OAB) symptoms affect daily life by decreasing health-related quality of life (HRQol). However, there remain no very effective treatment for OAB. Pharmacotherapy is one of the best treatment...
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Article
A comparison of laparoendoscopic single-site surgery versus conventional procedures for laparoscopic donor nephrectomy: a Japanese multi-institutional retrospective study
Laparoendoscopic single-site donor nephrectomy (LESSDN) is a feasible and effective procedure because of its non-invasiveness and better cosmetic outcomes. However, there have been few multi-institutional stud...
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Article
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
The overwhelming majority of participants in current genetic studies are of European ancestry. To elucidate disease biology in the East Asian population, we conducted a genome-wide association study (GWAS) wit...