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  1. No Access

    Article

    Prognostic Significance of Tumor-Associated Inflammation in Renal Cell Carcinoma

    This study analyzed tumor-associated inflammation by assessing the expression of cyclophilin A (CypA) and TNF in samples of kidney tumors of various histological types. It was shown that different histological...

    O. V. Kovaleva, P. A. Podlesnaya… in Bulletin of Experimental Biology and Medic… (2024)

  2. No Access

    Article

    Soluble B7-H3 in Colorectal Cancer

    We present the results of comparative ELISA of the concentration of soluble form of immunity checkpoint B7-H3 (sB7-H3) in the serum of patients with colorectal cancer (CRC) at different stages before treatment...

    O. V. Kovaleva, A. N. Gratchev… in Bulletin of Experimental Biology and Medic… (2023)

  3. No Access

    Article

    Clinical Significance of CD66b Expression in Non-Small Cell Lung Cancer

    We studied the expression of CD66b (a protein of the cancer-embryonic antigen family, expressed mainly in neutrophils) in tumor and stromal cells of non-small cell lung cancer (93 samples). The number of CD66b+ n...

    O. V. Kovaleva, P. A. Podlesnaya… in Bulletin of Experimental Biology and Medic… (2023)

  4. No Access

    Article

    Transcriptome of Lung Cancer Cells Resistant to the Cytotoxic Activity of Macrophages

    The role of the immune system in tumor progression has been the subject of research for more than 100 years since Paul Ehrlich hypothesized that the presence of the immune system limits the occurrence of cance...

    O. V. Kovaleva, P. A. Podlesnaya, M. V. Vasileva… in Doklady Biochemistry and Biophysics (2022)

  5. No Access

    Article

    Cytotoxic Activity of Macrophages as a Tumor Malignancy Factor

    An experimental cell-based model was developed to study antibody-independent cytotoxic activity of macrophages that allows selection of derivative tumor cells resistant to this activity and clarification of th...

    P. A. Podlesnaya, O. V. Kovaleva… in Bulletin of Experimental Biology and Medic… (2022)

  6. No Access

    Article

    The Mechanism of the Development of Macrophage Tolerance in Tumor Microenvironment

    Bacteria forming the resident microbiome of the tumor are an integral component of its microenvironment. The interaction of the tumor microbiome with the tumor or tumor stromal cells is not well understood. We...

    P. A. Podlesnaya, O. V. Kovaleva… in Bulletin of Experimental Biology and Medic… (2022)

  7. No Access

    Article

    Soluble B7-H3 in Ovarian Cancer and Its Predictive Value

    The content of the soluble form of protein of the key point of immunity B7-H3 (sB7-H3) in the blood plasma of 75 patients with epithelial ovarian cancer before treatment was measured by ELISA. It is known that...

    O. V. Kovaleva, T. P. Belova… in Bulletin of Experimental Biology and Medic… (2021)

  8. No Access

    Article

    Immunosuppression Factors PD-1, PD-L1, and IDO1 and Colorectal Cancer

    Due to the low efficiency of immunotherapy for colorectal cancer (CRC), it is extremely promising and relevant to study the mechanisms of immunosuppression. In this work, a comprehensive study of the expressio...

    O. V. Kovaleva, M. A. Rashidova, A. N. Gratchev… in Doklady Biochemistry and Biophysics (2021)

  9. No Access

    Article

    Expression of Transcription Factor PU.1 in Stromal Cells as a Prognostic Marker in Non-Small Cell Lung Cancer

    Transcription factor PU.1 is involved in hematopoiesis and is expressed in various cells of the inflammatory infiltrate of the tumor stroma, mainly in macrophages. The expression of PU.1 in 100 samples of non-...

    O. V. Kovaleva, M. A. Rashidova… in Bulletin of Experimental Biology and Medic… (2021)

  10. No Access

    Article

    Nanostructurization in X-ray amorphous organic substances of geological origin

    The nanosized structures of natural X-ray amorphous organic substances were examined with the use of atomic-force microscopy. The supramolecular structure types and particle sizes of natural solid bitumens fro...

    E. A. Golubev, O. V. Kovaleva in Russian Journal of General Chemistry (2011)

  11. No Access

    Article

    Genes potentially associated with resistance of lung cancer cells to paclitaxel

    K. N. Kashkin, E. A. Musatkina, A. V. Komelkov… in Doklady Biochemistry and Biophysics (2011)

  12. No Access

    Article

    Arf6, RalA, and BIRC5 protein expression in nonsmall cell lung cancer

    Evaluation of tumor marker expression pattern that determines individual progression parameters is one of the major topics in molecular oncopathology research. This work represents research on expression analy...

    A. V. Knizhnik, O. V. Kovaleva, K. K. Laktionov, V. V. Mochalnikova… in Molecular Biology (2011)

  13. No Access

    Article

    Expression profiling and putative mechanisms of resistance to doxorubicin of human lung cancer cells

    K. N. Kashkin, E. A. Musatkina, A. V. Komelkov… in Doklady Biochemistry and Biophysics (2010)

  14. No Access

    Article

    Transformation of the molecular and supramolecular structure of ozokerite under thermal effect

    The transformation of the molecular and supramolecular structure under the thermal effect of ozokerites from the Yarega, Russia; the Borislav, Ukraine; and the Shorsu, Uzbekistan deposits was studied. The elem...

    O. V. Kovaleva, E. A. Golubev in Geology of Ore Deposits (2009)

  15. No Access

    Article

    Membrane photocatalytic destruction of benzothiazoles in an aqueous medium

    The paper has described an improved type of a hybrid photocatalytic reactor based on ceramic membrane elements of cardierite and creation on its surface of catalytically active metal-oxide coatings of Ni, Ni-W...

    O. V. Kovaleva, G. G. Duka, V. V. Kovalev… in Journal of Water Chemistry and Technology (2009)

  16. No Access

    Article

    Microbarograph

    The microbarograph of a new design has been offered, and the general principle of its operation is considered. The microbarograph is distinguished from well-known ones; it incorporates a compensatory spring el...

    D. G. Gridnev, K. Kh. Kanonidi, Kh. D. Kanonidi, O. V. Kovaleva… in Seismic Instruments (2008)

  17. No Access

    Chapter and Conference Paper

    Study of Organic Mineralogical Matter by Scanning Probe Microscopy

    Among products of geological processes in the context of occurrence and variety of nanosize structural elements of natural, roentgenoamorphous, organic substances are most interesting objects [1, 2]. Nanosize ...

    Ye. A. Golubev, O. V. Kovaleva in EMC 2008 14th European Microscopy Congress… (2008)

  18. No Access

    Article

    On a Characterization of Monounary Algebras by their Endomorphism Semigroups

    A class of infinite monounary algebras without cyclic elements and such that the operations on these algebras are surjective is considered. It is proved that monounary algebras of this class are determined up ...

    B.V. Popov, O.V. Kovaleva in Semigroup Forum (2006)

  19. No Access

    Article

    Influence of radiation on the molecular structure of natural solid bitumens

    O. V. Kovaleva, N. P. Yushkin in Doklady Earth Sciences (2006)

  20. No Access

    Article

    Petroglyphs of the Barsuchy Log mound

    O. V. Kovaleva in Archaeology, Ethnology and Anthropology of Eurasia (2006)

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