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  1. No Access

    Article

    Insulin receptor variants and obesity-related cancers in the Framingham Heart Study

    The insulin-signaling pathway plays a pivotal role in cancer biology; however, evidence of genetic alterations in human studies is limited. This case–control study nested within the Framingham Heart Study (FHS...

    Niyati Parekh, Guia Guffanti, Yong Lin, Heather M. Ochs-Balcom… in Cancer Causes & Control (2015)

  2. No Access

    Article

    Concordance with World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guidelines for cancer prevention and obesity-related cancer risk in the Framingham Offspring cohort (1991–2008)

    This prospective cohort study evaluates associations between healthful behaviors consistent with WCRF/AICR cancer prevention guidelines and obesity-related cancer risk, as a third of cancers are estimated to b...

    Nour Makarem, Yong Lin, Elisa V. Bandera, Paul F. Jacques… in Cancer Causes & Control (2015)

  3. No Access

    Article

    Racial differences in the association of insulin-like growth factor pathway and colorectal adenoma risk

    Insulin resistance is believed to play an important role in the link between energy imbalance and colon carcinogenesis. Emerging evidence suggests that there are substantial racial differences in genetic and a...

    Heather M. Ochs-Balcom, Caila B. Vaughn, **g Nie, Zhengyi Chen… in Cancer Causes & Control (2014)

  4. No Access

    Article

    Consumption of sugary foods and drinks and risk of endometrial cancer

    Consumption of foods high in sugar promotes insulin production, which has been linked to endometrial carcinogenesis. We evaluated the impact of dietary intake of sugary foods and beverages, as well as added su...

    Melony G. King, Urmila Chandran, Sara H. Olson, Kitaw Demissie… in Cancer Causes & Control (2013)

  5. No Access

    Article

    Diabetes mellitus as a risk factor for gastrointestinal cancers among postmenopausal women

    While diabetes has been linked to several cancers in the gastrointestinal (GI) tract, findings have been mixed for sites other than colorectal and liver cancer. We used the Women’s Health Initiative (WHI) data...

    Juhua Luo, Rowan Chlebowski, Simin Liu, Katherine A. McGlynn… in Cancer Causes & Control (2013)

  6. No Access

    Article

    Longitudinal associations of blood markers of insulin and glucose metabolism and cancer mortality in the third National Health and Nutrition Examination Survey

    Insulin and glucose may influence cancer mortality via their proliferative and anti-apoptotic properties. Using longitudinal data from the nationally representative Third National Health and Nutrition Examinat...

    Niyati Parekh, Yong Lin, Richard B. Hayes, Jeanine B. Albu… in Cancer Causes & Control (2010)