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Article
Open AccessTrends in chemotherapy use for early-stage breast cancer from 2006 to 2019
Little is known about how use of chemotherapy has evolved in breast cancer patients. We therefore describe chemotherapy patterns for women with stage I-IIIA breast cancer in the Optimal Breast Cancer Chemother...
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Article
Open AccessCD163+ macrophages in the triple-negative breast tumor microenvironment are associated with improved survival in the Women’s Circle of Health Study and the Women’s Circle of Health Follow-Up Study
Tumor-associated macrophages (TAMs) are a prominent immune subpopulation in the tumor microenvironment that could potentially serve as therapeutic targets for breast cancer. Thus, it is important to characteri...
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Article
COVID-19 perceptions, impacts, and experiences: a cross-sectional analysis among New Jersey cancer survivors
Cancer survivors are particularly vulnerable to adverse COVID-19-related outcomes, but limited data exist on perceptions about the pandemic and related experiences in this group.
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Article
Open AccessComparing patient-reported outcomes and lifestyle factors before and after the COVID-19 pandemic among Black and Hispanic breast cancer survivors in New Jersey
The impact of the COVID-19 pandemic restrictions in the US since March 2020 on cancer survivorship among Black and Hispanic breast cancer (BC) survivors remains largely unknown. We aimed to evaluate associatio...
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Article
Assessment of breast cancer chemotherapy dose reduction in an integrated healthcare delivery system
Most cytotoxic drugs are dosed using body surface area (BSA), yet not all cancer patients receive the full BSA-determined dose. Prior work suggests that breast cancer patients who are obese are more likely to ...
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Article
Menopausal hormone therapy use and risk of ovarian cancer by race: the ovarian cancer in women of African ancestry consortium
Most studies examining post-menopausal menopausal hormone therapy (MHT) use and ovarian cancer risk have focused on White women and few have included Black women.
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Article
Association of inflammation-related exposures and ovarian cancer survival in a multi-site cohort study of Black women
An association was observed between an inflammation-related risk score (IRRS) and worse overall survival (OS) among a cohort of mostly White women with invasive epithelial ovarian cancer (EOC). Herein, we eval...
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Article
mTOR pathway candidate genes and energy intake interaction on breast cancer risk in Black women from the Women’s Circle of Health Study
Excessive energy intake has been shown to affect the mammalian target of the rapamycin (mTOR) signaling pathway and breast cancer risk. It is not well understood whether there are gene-environment interactions...
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Article
Open AccessFactors associated with health-related quality of life in a cohort of cancer survivors in New Jersey
Although there is extensive literature on correlates of health-related quality of life (HRQoL) among cancer survivors, there has been less attention paid to the role of socioeconomic disadvantage and survivors...
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Article
mTOR pathway candidate genes and obesity interaction on breast cancer risk in black women from the Women’s Circle of Health Study
Obesity is known to stimulate the mammalian target of rapamycin (mTOR) signaling pathway and both obesity and the mTOR signaling pathway are implicated in breast carcinogenesis. We investigated potential gene-...
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Article
mTOR pathway candidate genes and physical activity interaction on breast cancer risk in black women from the women’s circle of health study
Physical activity has been shown to affect the mammalian target of rapamycin (mTOR) signaling pathway and consequently breast carcinogenesis. Given that Black women in the USA are less physically active, it is...
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Article
Open AccessSurvival of epithelial ovarian cancer in Black women: a society to cell approach in the African American cancer epidemiology study (AACES)
The causes for the survival disparity among Black women with epithelial ovarian cancer (EOC) are likely multi-factorial. Here we describe the African American Cancer Epidemiology Study (AACES), the largest coh...
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Impact of Obesity and Related Factors in Breast Cancer Survivorship Among Hispanic Women
Breast cancer is the leading cause of death among Hispanic women. The number of Hispanic breast cancer survivors is increasing because the US Hispanic population is fast-growing and breast cancer survival is i...
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Article
Spirituality and financial toxicity among Hispanic breast cancer survivors in New Jersey
Cancer survivors often incur significant out-of-pocket costs; this can result in financial toxicity, defined as the adverse financial impact of cancer due to direct or indirect costs related to the disease. Th...
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Article
Phenols, Parabens, Phthalates and Puberty: a Systematic Review of Synthetic Chemicals Commonly Found in Personal Care Products and Girls’ Pubertal Development
Exposure to endocrine disrupting chemicals through personal care products (PCPs) is widespread and may disrupt hormone-sensitive endpoints, such as timing of puberty. Given the well-documented (and ongoing) de...
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Article
Racial differences in the association of body mass index and ovarian cancer risk in the OCWAA Consortium
Obesity disproportionately affects African American (AA) women and has been shown to increase ovarian cancer risk, with some suggestions that the association may differ by race.
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Article
Open AccessmTOR pathway gene expression in association with race and clinicopathological characteristics in Black and White breast cancer patients
Aberrant activation of the mammalian Target of Rapamycin (mTOR) pathway has been linked to obesity and endocrine therapy resistance, factors that may contribute to Black-White disparities in breast cancer outc...
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Article
Open AccessPathways between objective and perceived neighborhood factors among Black breast cancer survivors
Mounting evidence supports associations between objective neighborhood disorder, perceived neighborhood disorder, and health, yet alternative explanations involving socioeconomic and neighborhood social cohesi...
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Article
Financial hardship among cancer survivors in Southern New Jersey
To identify predictors of financial hardship, operationalized as foregoing health care, making financial sacrifices, and being concerned about having inadequate financial and insurance information.
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Article
Open AccessBody fatness and breast cancer risk in relation to phosphorylated mTOR expression in a sample of predominately Black women
The mechanistic target of rapamycin (mTOR) pathway promoted by positive energy imbalance and insulin-like growth factors can be a mechanism by which obesity influences breast cancer risk. We evaluated the asso...
