22 Result(s)
within
Heather M. Ochs-Balcom
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Article
Sleep duration and mortality among breast cancer survivors in the Western New York Exposures and Breast Cancer (WEB) Study
There is increasing evidence that sleep duration may affect breast cancer survival through effects on circadian function, influencing disease progression. However, further investigation of this association is ...
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Menopausal hormone therapy use and risk of ovarian cancer by race: the ovarian cancer in women of African ancestry consortium
Most studies examining post-menopausal menopausal hormone therapy (MHT) use and ovarian cancer risk have focused on White women and few have included Black women.
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Prevalence of Shared Decision-making in Prostate Cancer Screening in New York State
Current guidelines recommend that physicians use a shared decision-making (SDM) approach to engage with patients on the potential benefits and harms of prostate cancer screening based on their individual risk....
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Follicle-stimulating hormone is associated with low bone mass in postmenopausal women
We evaluated the influence of two endogenous hormones on bone health in older women. Higher FSH was associated with bone disease, especially in lower estradiol environments. FSH attenuated the relationship bet...
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Open AccessAn integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling
Sleep Disordered Breathing (SDB) is a common disease associated with increased risk for cardiometabolic, cardiovascular, and cognitive diseases. How SDB affects the molecular environment is still poorly unders...
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Racial differences in the association of body mass index and ovarian cancer risk in the OCWAA Consortium
Obesity disproportionately affects African American (AA) women and has been shown to increase ovarian cancer risk, with some suggestions that the association may differ by race.
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Open AccessAssociation of sleep duration and insomnia with metabolic syndrome and its components in the Women’s Health Initiative
Epidemiological evidence suggests that inadequate sleep duration and insomnia may be associated with increased risk of metabolic syndrome (MetS). However, longitudinal data with repeated measures of sleep dura...
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Open AccessEffect of musculature on mortality, a retrospective cohort study
While often life-saving, treatment for head and neck cancer (HNC) can be debilitating resulting in unplanned hospitalization. Hospitalizations in cancer patients may disrupt treatment and result in poor outcom...
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Cross-sectional analysis of myosteatosis and physical function in pretreatment head and neck cancer patients
Head and neck cancer (HNC) and its treatment are associated with muscle weakness and considerable long-term comorbidity. The goal of this study was to determine whether skeletal muscle density (SMD) as quantif...
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Article
Downstaging of cervical cancer in Tanzania over a 16-year period
Globally, the highest cervical cancer mortality rates are found in East Africa. Visual inspection with acetic acid (VIA)-based screening in resource-poor settings has been shown to decrease the proportion of w...
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Ovarian Cancer in Women of African Ancestry (OCWAA) consortium: a resource of harmonized data from eight epidemiologic studies of African American and white women
Although the incidence rate of epithelial ovarian cancer (EOC) is somewhat lower in African American (AA) than white women, survival is worse. The Ovarian Cancer in Women of African Ancestry (OCWAA) consortium...
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Admixture map** and fine-map** of birth weight loci in the Black Women’s Health Study
Several genome-wide association studies (GWAS) have identified genetic variants associated with birth weight. To date, however, most GWAS of birth weight have focused primarily on European ancestry samples eve...
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Sleep quality, duration, and breast cancer aggressiveness
Epidemiological studies suggest that short sleep duration and poor sleep quality may increase breast cancer risk. However, whether sleep is associated with breast tumor aggressiveness characteristics has large...
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Open AccessIntegration of VDR genome wide binding and GWAS genetic variation data reveals co-occurrence of VDR and NF-κB binding that is linked to immune phenotypes
The nuclear hormone receptor superfamily acts as a genomic sensor of diverse signals. Their actions are often intertwined with other transcription factors. Nuclear hormone receptors are targets for many therap...
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Adiposity is associated with p53 gene mutations in breast cancer
Mutations in the p53 gene are among the most frequent genetic events in human cancer and may be triggered by environmental and occupational exposures. We examined the association of clinical and pathological c...
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Insulin receptor variants and obesity-related cancers in the Framingham Heart Study
The insulin-signaling pathway plays a pivotal role in cancer biology; however, evidence of genetic alterations in human studies is limited. This case–control study nested within the Framingham Heart Study (FHS...
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Dietary lignan intake and androgen receptor expression in breast tumors
Lignans, a class of phytoestrogen commonly found in the Western diet, have been linked to decreased breast cancer risks in epidemiologic studies. Similar to estrogen receptors, the androgen receptor (AR), a pr...
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“It takes a village”: multilevel approaches to recruit African Americans and their families for genetic research
One barrier to searching for novel mutations in African American families with breast cancer is the challenge of effectively recruiting families—affected and non-affected relatives—into genetic research studie...
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Racial differences in the association of insulin-like growth factor pathway and colorectal adenoma risk
Insulin resistance is believed to play an important role in the link between energy imbalance and colon carcinogenesis. Emerging evidence suggests that there are substantial racial differences in genetic and a...
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Establishing a community partnership to optimize recruitment of African American pedigrees for a genetic epidemiology study
We developed a breast cancer genetic epidemiology study in collaboration with a community partnership to optimize recruitment and participation of African American women. We recognized that recruitment of rela...
