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Article
Open AccessGenomic and morphological characterization of Knufia obscura isolated from the Mars 2020 spacecraft assembly facility
Members of the family Trichomeriaceae, belonging to the Chaetothyriales order and the Ascomycota phylum, are known for their capability to inhabit hostile environments characterized by extreme temperatures, oligo...
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Article
Open AccessPhylogenomics, phenotypic, and functional traits of five novel (Earth-derived) bacterial species isolated from the International Space Station and their prevalence in metagenomes
With the advent of long-term human habitation in space and on the moon, understanding how the built environment microbiome of space habitats differs from Earth habitats, and how microbes survive, proliferate a...
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Article
Widespread increases in soluble phosphorus concentrations in streams across the transboundary Great Lakes Basin
Excess phosphorus from agricultural intensification has contributed to the eutrophication of rivers and lakes worldwide, including the transboundary Laurentian Great Lakes Basin. Algal blooms have surged in th...
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Article
Open AccessGenomic characterization and radiation tolerance of Naganishia kalamii sp. nov. and Cystobasidium onofrii sp. nov. from Mars 2020 mission assembly facilities
During the construction and assembly of the Mars 2020 mission components at two different NASA cleanrooms, several fungal strains were isolated. Based on their colony morphology, two strains that showed yeast-...
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Article
Open AccessCharacterization of metagenome-assembled genomes from the International Space Station
Several investigations on the microbial diversity and functional properties of the International Space Station (ISS) environment were carried out to understand the influence of spaceflight conditions on the mi...
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Article
Open AccessMultidrug-resistant Acinetobacter pittii is adapting to and exhibiting potential succession aboard the International Space Station
Monitoring the adaptation of microorganisms to the extreme environment of the International Space Station (ISS) is crucial to understanding microbial evolution and infection prevention. Acinetobacter pittii is an...
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Article
Open AccessMachine learning algorithm to characterize antimicrobial resistance associated with the International Space Station surface microbiome
Antimicrobial resistance (AMR) has a detrimental impact on human health on Earth and it is equally concerning in other environments such as space habitat due to microgravity, radiation and confinement, especia...
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Article
The human factor in seasonal streamflows across natural and managed watersheds of North America
While it is established that climate change and human activities (for example, urbanization, dams) alter streamflows, there exists considerable uncertainty regarding the relative magnitude of their contributio...
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Article
Effect of the insect feeding deterrent 1-allyloxy-4-propoxybenzene on olfactory responses and host choice of Varroa destructor
The ectoparasitic mite, Varroa destructor Anderson and Trueman (Acar: Varroidae), is a major threat for the honey bee, Apis mellifera L. Varroa behavior and physiology are influenced by compounds produced by the ...
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Article
Open AccessA Granger causality analysis of groundwater patterns over a half-century
Groundwater depletion in many areas of the world has been broadly attributed to irrigation. However, more formal, data-driven, causal mechanisms of long-term groundwater patterns have not been assessed. Here, ...
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Article
Open AccessMulti-drug resistant Enterobacter bugandensis species isolated from the International Space Station and comparative genomic analyses with human pathogenic strains
The antimicrobial resistance (AMR) phenotypic properties, multiple drug resistance (MDR) gene profiles, and genes related to potential virulence and pathogenic properties of five Enterobacter bugandensis strains ...
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Article
Pervasiveness of UVC254-resistant Geobacillus strains in extreme environments
We have characterized a broad collection of extremophilic bacterial isolates from a deep subsurface mine, compost dum** sites, and several hot spring ecosystems. Spore-forming strains isolated from these env...
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Article
Open AccessChemosensing of honeybee parasite, Varroa destructor: Transcriptomic analysis
Chemosensing is a primary sense in nature, however little is known about its mechanism in Chelicerata. As a model organism we used the mite Varroa destructor, a key parasite of honeybees. Here we describe a trans...
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Article
Open AccessSparse feature selection for classification and prediction of metastasis in endometrial cancer
Metastasis via pelvic and/or para-aortic lymph nodes is a major risk factor for endometrial cancer. Lymph-node resection ameliorates risk but is associated with significant co-morbidities. Incidence in patient...
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Article
The chemical ecology of host-parasite interaction as a target of Varroa destructor control agents
Honey bees and their ectoparasite Varroa destructor communicate through chemical signals among themselves, but they also eavesdrop on each other’s chemical cues. We summarize semiochemicals of honey bees and Varr...
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Article
Computational studies on molecular interactions of 6-thioguanosine analogs with anthrax toxin receptor 1
Dormant endospores of Bacillus anthracis are the causative agent of anthrax, which is an acute disease for both human and animals. Anthrax has been practised as biological weapon because of two attributes: i) sho...
