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    Article

    Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice

    Reduced hyaluronan–TLR4 signaling in a stem cell population of the lung contributes to a lack of renewal of these cells and promotes fibrosis in patients with idiopathic pulmonary fibrosis.

    Jiurong Liang, Yanli Zhang, Ting **e, Ningshan Liu, Huaiyong Chen in Nature Medicine (2016)

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    Open Access

    Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo

    Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease. Although the pathogenesis is poorly understood, evidence suggests that genetic and epigenetic alterations, such as DNA methylation, may play a...

    Caijuan Huan, Ting Yang, Jiurong Liang, Ting **e, Luis Cheng in Scientific Reports (2015)