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Article
Open AccessGasdermin D deficiency aborts myeloid calcium influx to drive granulopoiesis in lupus nephritis
Gasdermin D (GSDMD) is emerging as an important player in autoimmune diseases, but its exact role in lupus nephritis (LN) remains controversial. Here, we identified markedly elevated GSDMD in human and mouse L...
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Article
Study on the relationship between interface morphology and mechanical properties of explosive welded titanium/duplex stainless steel
This study investigated the interface morphology and mechanical properties of titanium (TP 270C)/duplex stainless steel (SUS 821L1) near the lower limit of the explosive welding window. Seven samples with diff...
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Article
Open AccessElectroacupuncture and carbamazepine for patients with trigeminal neuralgia: a randomized, controlled, 2 × 2 factorial trial
Trigeminal neuralgia (TN) is difficult to treat due to its severe pain intensity and recurring episodes, which significantly impact quality of life.
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Article
Open AccessIL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy in advanced gynecologic cancer
Tumor-infiltrating lymphocyte (TIL) therapy has been restricted by intensive lymphodepletion and high-dose intravenous interleukin-2 (IL-2) administration. To address these limitations, we conducted preclinica...
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Article
Interface Microstructure and Numerical Simulation Investigations of Ni/TC18 Composite Tube Fabricated by Explosive Welding
The larger diameter Ni/TC18 bimetallic composite tube was successfully manufactured by explosive welding. The bonding interface waveform structure and the distribution of interfacial elements were characterize...
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Article
Experimental study on dynamic crack growth and propagation characteristics of central hole double fracture shales under impact loading
It is greatly significant to evaluate the stability of the shales with characteristic defects that the propagation and crack initiation behavior under the dynamic impact. For studying the influence of bedding ...
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Article
Neutral color and self-healable electrochromic system based on CuI/Cu and \({{\rm{I}}_3}^ - /{{\rm{I}}^ - }\) conversions
The electrochromic (EC) mechanisms of inorganic materials are usually based on reversible cation insertion/extraction or metal deposition/dissolution, which are plagued by ion trap** and dendrite growth, res...
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Article
Analysis of Fracture Network Formation Mechanisms and Main Controlling Factors of Methane Explosion Fracturing in Deep Shale Reservoir
Methane in situ explosion fracturing can induce intricate fracture networks by detonating methane desorbed from deep shale reservoirs. Elucidating the fracture propagation mechanisms under high-pressure gas ex...
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Article
Triboelectric nanogenerator hybrid array driven by multiform natural energies and its applications in self-powered cathodic protection
In view of the increasing energy shortage and environmental pollution, the collection of friction charges to achieve the conversion of various natural energies and provide in-situ cathodic protection for metals i...
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Chapter and Conference Paper
Research on Metamodel-Driven Deployment Model for Converter Station Applications
Currently, the deployment of converter station applications faces some challenges, such as complex resource dependencies and long deployment cycles, which severely hinder the efficient operation of converter s...
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Chapter and Conference Paper
Locomotion in Response of Static Pedestrians in a Mixed Reality Environment
As the development of mixed reality technology, overlaying virtual objects onto the real environment using HMD has become a new and promising research tool, especially for pedestrian behavior and interaction. ...
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Chapter and Conference Paper
Improved Particle Swarm Optimization Based on Flexible Load Scheduling Method for New Energy Distribution Network
With the development of the energy market, new changes have emerged on the supply side, distribution side and energy use side of multi-energy supply energy networks, with more and more subjects joining them. W...
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Chapter and Conference Paper
Research on the Intensive Construction Plan of Edge Cluster for Digital Converter Station
Edge cluster construction is one of the key tasks in the digital transformation of converter stations. Traditional systems at the edge of converter stations suffer from issues such as independent, scattered so...
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Article
Open AccessMUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer
MUC16 (CA125) is a commonly used tumor marker for ovarian cancer screening and reported to be an immunosuppressive factor by acting on the sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on the sur...
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Article
Open AccessIdentification of TRPM2 as a prognostic factor correlated with immune infiltration in ovarian cancer
Ovarian cancer (OC) is one of the most common gynecologic malignant cancers with the current survival rate remaining low. TRPM2 has been reported as a survival predictor in various cancers but not in OC. The a...
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Article
Open AccessResearch Progress of Fever with Thrombocytopenia Syndrome
Severe fever with thrombocytopenia syndrome (SFTS) is a new infectious disease first discovered in Ta-pieh Mountains in central China in 2009. It is caused by a novel bunyavirus infection (SFTSV). Since the fi...
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Article
Open AccessChina can be self-sufficient in maize production by 2030 with optimal crop management
Population growth and economic development in China has increased the demand for food and animal feed, raising questions regarding China’s future maize production self-sufficiency. Here, we address this challe...
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Article
Open AccessA multicenter study of artificial intelligence-aided software for detecting visible clinically significant prostate cancer on mpMRI
AI-based software may improve the performance of radiologists when detecting clinically significant prostate cancer (csPCa). This study aims to compare the performance of radiologists in detecting MRI-visible ...
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Article
A novel hollow microsphere composite MnOx/PAA: effective catalyst for ozone decomposition at high humidity
Ozone air pollution poses a serious threat to human health and ecological environment. Manganese oxide (MnOx) is a popular material for ozone decomposition with excellent catalytic performance. However, the ca...
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Chapter and Conference Paper
Quality Coin for Software Quality Improvement
Modern Software has growing complexity. It puts higher quality requirements on continuous software development. Software quality is beyond pass rate and can be reflected by more perspectives in the whole devel...