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Article
No observable conformational changes in PSII
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Protocol
RNA Structure Refinement Using the ERRASER-Phenix Pipeline
The final step of RNA crystallography involves the fitting of coordinates into electron density maps. The large number of backbone atoms in RNA presents a difficult and tedious challenge, particularly when exp...
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Article
EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
The fit of atomic models of protein structures to high-resolution cryo-electron microscopy maps can be assessed with a validation tool, EMRinger.
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Article
Correction: Corrigendum: Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers
Nat. Methods 11, 545–548 (2014); published online 16 March 2014; corrected after print 3 June 2015 In the version of this article initially published, the authors claimed that with the tool cctbx.xfel, weak di...
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Article
Macromolecular X-ray structure determination using weak, single-wavelength anomalous data
An improved analysis approach for single-wavelength anomalous diffraction (SAD)-based macromolecular X-ray structure determination expands the applicability of this phasing method for macromolecules with weak ...
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Article
Taking snapshots of photosynthetic water oxidation using femtosecond X-ray diffraction and spectroscopy
The dioxygen we breathe is formed by light-induced oxidation of water in photosystem II. O2 formation takes place at a catalytic manganese cluster within milliseconds after the photosystem II reaction centre is e...
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Article
Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers
A computational approach and software tool, cctbx.xfel, enables the determination of accurate macromolecular structure factors using a relatively small number of serial femtosecond crystallography diffraction ...
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Article
Improved low-resolution crystallographic refinement with Phenix and Rosetta
An approach combining the sampling methodology and energy function of Rosetta with the X-ray refinement methodology of Phenix enables improved low-resolution crystallographic refinement.
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Article
Open Accessphenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta
The combination of algorithms from the structure-modeling field with those of crystallographic structure determination can broaden the range of templates that are useful for structure determination by the meth...
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Article
An integrated approach for finding overlooked genes in yeast
We report here the discovery of 137 previously unappreciated genes in yeast through a widely applicable and highly scalable approach integrating methods of gene-trap**, microarray-based expression analysis, ...