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  1. No Access

    Article

    Cellular Delivery of siRNA Using Poly(2-dimethylaminoethyl methacrylate)- Functionalized Graphene Oxide Nano-Wrap

    Despite its high therapeutic potential, the use of siRNA has still been limited mostly due to the lack of a proper delivery system. Small number of charges and inflexible structure of siRNA are the major facto...

    Jung Eun Lee, Kyuri Lee, Jeong A. Nam, Aesun Kim, So Young Lee… in Macromolecular Research (2018)

  2. No Access

    Article

    Micelle-templated dendritic gold nanoparticles for enhanced cellular delivery of siRNA

    Successful cellular delivery of synthetic siRNA depends mainly on the capability of a carrier to form a stable complex with siRNA, which can provide efficient protection of the siRNA from enzyme-mediated degra...

    Min Sang Lee, Nak Won Kim, Jung Eun Lee, Dong Woo Lim… in Macromolecular Research (2015)

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    Article

    Enhanced Transfection by Antioxidative Polymeric Gene Carrier that Reduces Polyplex-Mediated Cellular Oxidative Stress

    To test the hypothesis in which polyplex-induced oxidative stress may affect overall transfection efficiency, an antioxidative transfection system minimizing cellular oxidative stress was designed for enhanced...

    Min Sang Lee, Nak Won Kim, Kyuri Lee, Hongtae Kim, Ji Hoon Jeong in Pharmaceutical Research (2013)