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  1. Article

    Open Access

    A single-tube multiparameter seven-colour flow cytometry strategy for the detection of malignant plasma cells in multiple myeloma

    N Robillard, M C Béné, P Moreau, S Wuillème in Blood Cancer Journal (2013)

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  2. Article

    Open Access

    Autocrine insulin-like growth factor 1 and stem cell factor but not interleukin 6 support self-renewal of human myeloma cells

    In this study, we have identified the growth factors supporting myeloma self-renewal in eight myeloma cell lines. All cell lines able to form self-colonies displayed constitutive P-AKT and P-ERK1,2 but not P-S...

    D Chiron, S Maïga, S Surget, G Descamps, P Gomez-Bougie, S Traore… in Blood Cancer Journal (2013)

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  3. No Access

    Article

    Flow cytometry and IG/TCR quantitative PCR for minimal residual disease quantitation in acute lymphoblastic leukemia: a French multicenter prospective study on behalf of the FRALLE, EORTC and GRAALL

    Minimal residual disease (MRD) quantification is widely used for therapeutic stratification in pediatric acute lymphoblastic leukemia (ALL). A robust, reproducible, sensitivity of at least 0.01% has been achie...

    R Garand, K Beldjord, H Cavé, C Fossat, I Arnoux, V Asnafi, Y Bertrand… in Leukemia (2013)

  4. No Access

    Article

    Simultaneous study of five candidate target antigens (CD20, CD22, CD33, CD52, HER2) for antibody-based immunotherapy in B-ALL: a monocentric study of 44 cases

    P Chevallier, N Robillard, G Houille, S Ayari, T Guillaume, J Delaunay… in Leukemia (2009)

  5. No Access

    Article

    Rituximab in CD20 positive multiple myeloma

    P Moreau, L Voillat, L Benboukher, C Mathiot, C Dumontet, N Robillard… in Leukemia (2007)

  6. No Access

    Article

    CD33 is expressed on plasma cells of a significant number of myeloma patients, and may represent a therapeutic target

    N Robillard, S Wuillème, L Lodé, F Magrangeas, S Minvielle, H Avet-Loiseau in Leukemia (2005)

  7. No Access

    Article

    Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival

    We and others have shown that Mcl-1 was essential for the survival of human myeloma cells in vitro. Furthermore, this antiapoptotic protein is upregulated by interleukin-6, which plays a critical role in multiple...

    S Wuillème-Toumi, N Robillard, P Gomez, P Moreau, S Le Gouill, H Avet-Loiseau… in Leukemia (2005)

  8. No Access

    Article

    Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma

    Ploidy appears as an important parameter in both the biology and the clinical evolution of multiple myeloma. However, its evaluation requires either a successful karyoty** (obtained in 30% of the patients) o...

    S Wuilleme, N Robillard, L Lodé, F Magrangeas, H Beris, J-L Harousseau… in Leukemia (2005)

  9. No Access

    Article

    Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells

    R115777, a nonpeptidomimetic farnesyl transferase inhibitor has recently demonstrated a significant antileukemic activity in vivo in acute myeloid leukemia. Multiple myeloma (MM) is a fatal hematological malignan...

    S Le Gouill, C Pellat-Deceunynck, J-L Harousseau, M-J Rapp, N Robillard… in Leukemia (2002)

  10. No Access

    Article

    Use of pathology-specific peripheral blood CD34 thresholds to predict leukapheresis CD34 content with optimal accuracy: a bicentric analysis of 299 leukaphereses

    CD34+ cell counts in peripheral blood (PB) and corresponding numbers of CD34+ cells and colony-forming units-granulocyte/macrophage (CFU-GM) in 299 leukapheresis products of 209 patients undergoing PB progeni...

    I. Dobo, N. Robillard, D. Pineau, F. Geneviève, N. Piard… in Annals of Hematology (2001)

  11. No Access

    Article

    Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy

    Multiple myeloma (MM) is a malignancy characterized by a very slow proliferation of malignant plasma cells leading to their accumulation within the bone marrow. This suggests that resistance to apoptosis may p...

    D Puthier, C Pellat-Deceunynck, S Barillé, N Robillard, M-J Rapp… in Leukemia (1999)

  12. No Access

    Article

    The absence of CD56 (NCAM) on malignant plasma cells is a hallmark of plasma cell leukemia and of a special subset of multiple myeloma

    In this study, we show that malignant plasma cells from patients with either primary (n = 12) or secondary (n = 15) plasma cell leukemia (PCL) do not express CD56 at all, neither in the bone marrow nor the periph...

    C Pellat-Deceunynck, S Barillé, G Jego, D Puthier, N Robillard, D Pineau… in Leukemia (1998)

  13. No Access

    Article

    Effects of bistramide A on a non-small-cell bronchial carcinoma line

    The antiproliferative effects of bistramide A, a nitrogenous dilactam polyether fromLissoclinum bistratum Sluiter (Urochordata), were studied at the level of the cell cycle in asynchronous cells of the NSCLCN6-L1...

    C. Roussakis, N. Robillard, D. Riou, J. F. Biard… in Cancer Chemotherapy and Pharmacology (1991)

  14. No Access

    Article

    Endothelial cell growth regulation by PGE1 analog misoprostol and indomethacin

    The role of prostaglandins on growth regulation of different cell types was investigated. We studied the effect of exogenous misoprostol in the presence or absence of indomethacin on the cell growth kinetics. .....

    Dr. T. Patrice MD, J. Harb PhD, M. T. Foultier… in Digestive Diseases and Sciences (1989)