20 Result(s)

Article

Lymphocyte expansion after unrelated cord blood allogeneic stem cell transplantation in adults

Limited information is available regarding the incidence and features of lymphocyte expansions after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Large granular lymphocytes (LGL) expansions ...

Y Le Bris, T Guillaume, A Ménard, M Illiaquer, J Martin… in Bone Marrow Transplantation (2017)

Article

Assessment of tumoral plasma cells in apheresis products for autologous stem cell transplantation in multiple myeloma

S Wuillème, A Lok, N Robillard, P Dupuis, V Stocco, H Migné… in Bone Marrow Transplantation (2016)

Article

Flow cytometry and IG/TCR quantitative PCR for minimal residual disease quantitation in acute lymphoblastic leukemia: a French multicenter prospective study on behalf of the FRALLE, EORTC and GRAALL

Minimal residual disease (MRD) quantification is widely used for therapeutic stratification in pediatric acute lymphoblastic leukemia (ALL). A robust, reproducible, sensitivity of at least 0.01% has been achie...

R Garand, K Beldjord, H Cavé, C Fossat, I Arnoux, V Asnafi, Y Bertrand… in Leukemia (2013)

Article

Simultaneous study of five candidate target antigens (CD20, CD22, CD33, CD52, HER2) for antibody-based immunotherapy in B-ALL: a monocentric study of 44 cases

P Chevallier, N Robillard, G Houille, S Ayari, T Guillaume, J Delaunay… in Leukemia (2009)

Article

Rituximab in CD20 positive multiple myeloma

P Moreau, L Voillat, L Benboukher, C Mathiot, C Dumontet, N Robillard… in Leukemia (2007)

Article

CD33 is expressed on plasma cells of a significant number of myeloma patients, and may represent a therapeutic target

N Robillard, S Wuillème, L Lodé, F Magrangeas, S Minvielle, H Avet-Loiseau in Leukemia (2005)

Article

Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival

We and others have shown that Mcl-1 was essential for the survival of human myeloma cells in vitro. Furthermore, this antiapoptotic protein is upregulated by interleukin-6, which plays a critical role in multiple...

S Wuillème-Toumi, N Robillard, P Gomez, P Moreau, S Le Gouill, H Avet-Loiseau… in Leukemia (2005)

Article

Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma

Ploidy appears as an important parameter in both the biology and the clinical evolution of multiple myeloma. However, its evaluation requires either a successful karyoty** (obtained in 30% of the patients) o...

S Wuilleme, N Robillard, L Lodé, F Magrangeas, H Beris, J-L Harousseau… in Leukemia (2005)

Article

Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells

R115777, a nonpeptidomimetic farnesyl transferase inhibitor has recently demonstrated a significant antileukemic activity in vivo in acute myeloid leukemia. Multiple myeloma (MM) is a fatal hematological malignan...

S Le Gouill, C Pellat-Deceunynck, J-L Harousseau, M-J Rapp, N Robillard… in Leukemia (2002)

Article

Use of pathology-specific peripheral blood CD34 thresholds to predict leukapheresis CD34 content with optimal accuracy: a bicentric analysis of 299 leukaphereses

CD34+ cell counts in peripheral blood (PB) and corresponding numbers of CD34+ cells and colony-forming units-granulocyte/macrophage (CFU-GM) in 299 leukapheresis products of 209 patients undergoing PB progeni...

I. Dobo, N. Robillard, D. Pineau, F. Geneviève, N. Piard… in Annals of Hematology (2001)

Article

Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy

Multiple myeloma (MM) is a malignancy characterized by a very slow proliferation of malignant plasma cells leading to their accumulation within the bone marrow. This suggests that resistance to apoptosis may p...

D Puthier, C Pellat-Deceunynck, S Barillé, N Robillard, M-J Rapp… in Leukemia (1999)

Article

The absence of CD56 (NCAM) on malignant plasma cells is a hallmark of plasma cell leukemia and of a special subset of multiple myeloma

In this study, we show that malignant plasma cells from patients with either primary (n = 12) or secondary (n = 15) plasma cell leukemia (PCL) do not express CD56 at all, neither in the bone marrow nor the periph...

C Pellat-Deceunynck, S Barillé, G Jego, D Puthier, N Robillard, D Pineau… in Leukemia (1998)

Article

Analysis of platelet recovery after autologous transplantation with G-CSF mobilized CD34+ cells purified from leukapheresis products

Abstract. We studied platelet recovery in relation to graft content in CFUs and CD34+ cells in 31 patients with multiple myeloma (21) or non-Hodgkin lymphoma (10) receiving marrow-ablative therapy followed by ...

S. Hermouet, A.-E. Niaussat, A. Briec, D. Pineau… in Hematology and Cell Therapy (1997)

Article

Immunophenotypic characterization of acute leukemias and chronic lymphoproliferative disorders: practical recommendations and classifications

Immunophenotypic characterization of leukemic cells has become essential for the diagnosis of acute leukemias (AL) and chronic lymphoproliferative disorders (CLPD). Immunophenoty** allows to classify AL acco...

R. Garand, N. Robillard in Hematology and Cell Therapy (1996)

Article

Childhood B-cell acute lymphoblastic leukemia with FAB-L1 morphology and a t(9;11) translocation involving the MLL gene

The t(9;11)(p21–22;q23) translocation is frequently associated with acute monoblastic leukemia but may occasionally be seen in patients with acute lymphoblastic leukemia (ALL). We report a case of childhood AL...

P. Talmant, R. Berger, N. Robillard, F. Mechineau-Lacroix… in Hematology and Cell Therapy (1996)

Article

Effects of bistramide A on a non-small-cell bronchial carcinoma line

The antiproliferative effects of bistramide A, a nitrogenous dilactam polyether fromLissoclinum bistratum Sluiter (Urochordata), were studied at the level of the cell cycle in asynchronous cells of the NSCLCN6-L1...

C. Roussakis, N. Robillard, D. Riou, J. F. Biard… in Cancer Chemotherapy and Pharmacology (1991)

Chapter

The effect of test element size on performance of the D-15 in age-related maculopathy and congenital color deficiency

Most standard color vision tests have been designed to evaluate color vision of the central two degrees, since this is the visual region with greatest sensitivity to color differences. Consequently, low vision...

Kenneth Knoblauch, M. Fischer, N. Robillard, I. S. Grunwald… in Colour Vision Deficiencies X (1991)

Article

Endothelial cell growth regulation by PGE₁ analog misoprostol and indomethacin

The role of prostaglandins on growth regulation of different cell types was investigated. We studied the effect of exogenous misoprostol in the presence or absence of indomethacin on the cell growth kinetics. .....

Dr. T. Patrice MD, J. Harb PhD, M. T. Foultier… in Digestive Diseases and Sciences (1989)