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Article
Contributions of Genes and Environment to Developmental Change in Alcohol Use
The precise nature of how genetic and environmental risk factors influence changes in alcohol use (AU) over time has not yet been investigated. Therefore, the aim of the present study is to examine the nature ...
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Article
Open AccessCortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group
The neuro-anatomical substrates of major depressive disorder (MDD) are still not well understood, despite many neuroimaging studies over the past few decades. Here we present the largest ever worldwide study b...
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Article
Open AccessSubcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group
The aetiology of suicidal behaviour is complex, and knowledge about its neurobiological mechanisms is limited. Neuroimaging methods provide a noninvasive approach to explore the neural correlates of suicide vu...
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Open AccessResponse to Dr Fried & Dr Kievit, and Dr Malhi et al.
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Open AccessSubcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group
The pattern of structural brain alterations associated with major depressive disorder (MDD) remains unresolved. This is in part due to small sample sizes of neuroimaging studies resulting in limited statistica...
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Article
Open AccessGenome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium
Cannabis is the most widely produced and consumed illicit psychoactive substance worldwide. Occasional cannabis use can progress to frequent use, abuse and dependence with all known adverse physical, psycholog...
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Article
Contrast Effects and Sex Influence Maternal and Self-Report Dimensional Measures of Attention-Deficit Hyperactivity Disorder
The heritability of attention-deficit/hyperactivity disorder (ADHD) is higher for children than adults. This may be due to increasing importance of environment in symptom variation, measurement inaccuracy when...
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Article
Erratum: The genetics of addiction—a translational perspective
Correction to: Translational Psychiatry (2012) 2, e140; doi:10.1038/tp.2012.54; published online 17 July 2012 As the result of an editing error, two check marks were omitted from Box 1. In the ‘DSM-5’ column, ...
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Article
Open AccessThe genetics of addiction—a translational perspective
Addictions are serious and common psychiatric disorders, and are among the leading contributors to preventable death. This selective review outlines and highlights the need for a multi-method translational app...
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Article
Perceived social support in a large community sample
The positive health and wellbeing effects of social support have been consistently demonstrated in the literature since the late 1970s. However, a better understanding of the effects of age and sex is required.
