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Article
Open AccessA subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils
Rheumatoid arthritis (RA) involves several classes of pathogenic autoantibodies, some of which react with type-II collagen (COL2) in articular cartilage. We previously described a subset of COL2 antibodies tar...
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Article
Open AccessPlasma C4d as marker for lupus nephritis in systemic lupus erythematosus
In the present study, we sought to evaluate the complement activation product C4d as a marker for lupus nephritis in systemic lupus erythematosus (SLE).
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Article
Open AccessA subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources
Patients with systemic lupus erythematosus (SLE) have a decreased ability to clear cell remnants and multiple deficiencies in the ability to degrade cellular chromatin have been linked to the disease. Since th...
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Article
Open AccessDegradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus
The ability to degrade neutrophil extracellular traps (NETs) is reduced in a subset of patients with systemic lupus erythematosus (SLE). NETs consist of chromatin covered with antimicrobial enzymes and are nor...
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Article
Aminolysis of Aziridines Catalyzed by Samarium Iodides
Samarium diiodide is an efficient catalyst for the aminolysis of either activated or non activated aziridines with aromatic amines. A variety of N-diprotected β-diamines has been prepared including new products. ...
