-
Article
Open AccessA subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils
Rheumatoid arthritis (RA) involves several classes of pathogenic autoantibodies, some of which react with type-II collagen (COL2) in articular cartilage. We previously described a subset of COL2 antibodies tar...
-
Chapter and Conference Paper
Conf-UNet: A Model for Speculation on Unknown Oracle Bone Characters
Oracle Bone Characters (OBC) are the oldest developed pictographs in China, having been created over 3000 years ago. As a result of their antiquity and the scarcity of relevant historical sources, identifying ...
-
Article
Open AccessDual-function perovskite light-emitting/sensing devices for optical interactive display
Interactive display devices integrating multiple functions have become a development trend of display technology. The excellent luminescence properties of perovskite quantum dots (PQDs) make it an ideal lumine...
-
Article
Open AccessTwo cases of infantile-onset primary generalized glucocorticoid hypersensitivity and the effect of mifepristone
Primary generalized glucocorticoid hypersensitivity (PGGH) is a very rare disease caused by terminal organ hypersensitivity to glucocorticoids for which the aetiology is unknown. The incidence of PGGH is extre...
-
Article
Open AccessTwo major genes associated with autoimmune arthritis, Ncf1 and Fcgr2b, additively protect mice by strengthening T cell tolerance
A breach of T cell tolerance is considered as a major step in the pathogenesis of rheumatoid arthritis. In collagen-induced arthritis (CIA) model, immunization with type II collagen (COL2) leads to arthritis i...
-
Article
Ultrahigh-resolution quantum-dot light-emitting diodes
With the ever-growing demand for a greater number of pixels, next-generation displays have challenging requirements for resolution as well as colour gamut. Here, to meet this need, quantum-dot light-emitting d...
-
Article
Factors associated with treatment response to CD19 CAR-T therapy among a large cohort of B cell acute lymphoblastic leukemia
CD19-targeted chimeric antigen receptor (CAR) T cell therapy has demonstrated striking responses among B cell acute lymphoblastic leukemia (B-ALL), but analyses of potential factors associated with poor respon...
-
Chapter and Conference Paper
New Generation Power System Security Protection Technology Based on Dynamic Defense
With the development of power information systems and the evolution of attack means, the traditional security protection scheme is difficult to deal with the increasing network attacks. In order to deal with t...
-
Chapter and Conference Paper
A Method for Evaluating Health Status of Rail Transit Signaling Equipment Based on Group Decision
Aiming at the service lifetime and health status of signaling equipment that rail transit operators are concerned about, this paper proposes a method for evaluating the health status of signaling equipment bas...
-
Chapter and Conference Paper
Research on Music Genre Classification Based on Residual Network
With the rapid development of information technology, the number of songs is exploding, so the classification of music genres is a very challenging task, and at this stage, the implementation of automated clas...
-
Article
Open AccessFactors affecting bone maturation in Chinese girls aged 4–8 years with isolated premature thelarche
In isolated premature thelarche (IPT) girls, bone age (BA) is considered consistent with chronological age. However, some IPT girls confirmed by gonadotropin-releasing hormone (GnRH) stimulation test could sho...
-
Article
Open AccessInkjet-printed unclonable quantum dot fluorescent anti-counterfeiting labels with artificial intelligence authentication
An ideal anti-counterfeiting technique has to be inexpensive, mass-producible, nondestructive, unclonable and convenient for authentication. Although many anti-counterfeiting technologies have been developed, ...
-
Article
Open AccessUltrathin electronic synapse having high temporal/spatial uniformity and an Al2O3/graphene quantum dots/Al2O3 sandwich structure for neuromorphic computing
An electronic synapse (e-synapse) based on memristive switching is a promising electronic element that emulates a biological synapse to realize neuromorphic computing. However, the complex resistive switching ...
-
Article
Simple open-cavity pulsed Brillouin fiber laser with broadband supercontinuum generation
A simple open-cavity laser is proposed for supercontinuum generation. Broadband supercontinuum covering the wavelength from 630 to 1700 nm with low multimode LD pump power (~ 1.7 W) is demonstrated. Giant nano...
-
Article
Serum metabolomic study for detecting biomarkers of non-traumatic osteonecrosis of the femoral head
Non-traumatic osteonecrosis of the femoral head (NTONFH) is a progressive disease, always leading to hip dysfunction if no early intervention was applied. The difficulty for early diagnosis of NTONFH is due to...
-
Article
Open AccessMulti-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells
Chronic hepatitis B virus (HBV) infection is partly responsible for hepatitis, fatty liver disease and hepatocellular carcinoma (HCC). HBV core protein (HBc), encoded by the HBV genome, may play a significant ...
-
Article
Metabolic analysis of osteoarthritis subchondral bone based on UPLC/Q-TOF-MS
Osteoarthritis (OA), one of the most widespread musculoskeletal joint diseases among the aged, is characterized by the progressive loss of articular cartilage and continuous changes in subchondral bone. The ex...
-
Article
Metabolomic study of the bone trabecula of osteonecrosis femoral head patients based on UPLC–MS/MS
The severity and/or progression of osteonecrosis of the femoral head (ONFH) are commonly assessed by radiography, nuclear magnetic resonance image which aren’t invariably correlated to severity of disease and ...
-
Article
Open AccessRapid development of proteomics in China: from the perspective of the Human Liver Proteome Project and technology development
Proteomics focuses on the systematic identification and quantification of entire proteomes and interpretation of proteins’ biological functions. During the last decade, proteomics in China has grown much faste...
-
Chapter and Conference Paper
Initial State Modeling of Interlocking System Using Maude
In order to do formal verification of interlocking system, which is complicated but safety critical, we choose formal specification language Maude for modeling and verification based on membership equational l...
