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Open AccessEffectiveness of remote risk-based monitoring and potential benefits for combination with direct data capture
In recent years, alternative monitoring approaches, such as risk-based and remote monitoring techniques, have been recommended instead of traditional on-site monitoring to achieve more efficient monitoring. Re...
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Article
Open AccessCorrection to: Clinical characteristics and genetic backgrounds of Japanese patients with atypical hemolytic uremic syndrome
The original article can be found online
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Article
Open AccessClinical characteristics and genetic backgrounds of Japanese patients with atypical hemolytic uremic syndrome
Atypical hemolytic uremic syndrome (aHUS) is caused by complement overactivation, and its presentation and prognosis differ according to the underlying molecular defects. The aim of this study was to character...
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Article
Open AccessEffect of Oral Branched-Chain Amino Acids on Serum Albumin Concentration in Heart Failure Patients with Hypoalbuminemia: Results of a Preliminary Study
We conducted a randomized, controlled trial to determine whether supplementation with oral branched-chain amino acids (BCAAs) improves serum albumin and clinical outcomes in heart failure (HF) patients with hy...
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Article
Open AccessA multicenter, randomized controlled trial comparing the identification rate of stigmata of recent hemorrhage and rebleeding rate between early and elective colonoscopy in outpatient-onset acute lower gastrointestinal bleeding: study protocol for a randomized controlled trial
The clinical benefit of early colonoscopy within 24 h of arrival in patients with severe acute lower gastrointestinal bleeding (ALGIB) remains controversial. This trial will compare early colonoscopy (performe...
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Open AccessAn exploratory study on the efficacy and safety of a BCAA preparation used in combination with cardiac rehabilitation for patients with chronic heart failure
Sarcopenia is generally complicated with patients with chronic heart failure (CHF) and its presence negatively affects the course of heart failure, however effective nutritional intervention had not been eluci...
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Open AccessEnhancement of arterial pulsation during flow-mediated dilation is impaired in the presence of ischemic heart disease
The aim of this study is to investigate the relationship between arterial pulse amplitude change under increased shear stress and the presence of ischemic heart disease (IHD).
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Article
Brachial artery diameter has a predictive value in the improvement of flow-mediated dilation after aortic valve replacement for aortic stenosis
Aortic stenosis (AS) is the most common valvular disease and aortic valve replacement (AVR) is one of its most effective interventions. AS affects not only the left ventricle, but also vascular function beyond...
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Article
Impairment of flow-mediated dilation correlates with aortic dilation in patients with Marfan syndrome
Marfan syndrome is an inherited disorder characterized by genetic abnormality of microfibrillar connective tissue proteins. Endothelial dysfunction is thought to cause aortic dilation in subjects with a bicusp...
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Article
Diurnal body temperature rise is reduced in diabetes with autonomic neuropathy
We conducted a retrospective study of 60 patients with ischemic heart disease (31 with diabetes and 29 without diabetes) to investigate the impact of diabetes on diurnal body temperature patterns. We found tha...
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Article
Clinical correlation of brachial artery flow-mediated dilation in patients with systemic sclerosis
To investigate the clinical significance of flow-mediated dilation (FMD) in systemic sclerosis (SSc).