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Diurnal body temperature rise is reduced in diabetes with autonomic neuropathy

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Abstract

We conducted a retrospective study of 60 patients with ischemic heart disease (31 with diabetes and 29 without diabetes) to investigate the impact of diabetes on diurnal body temperature patterns. We found that the increase of axillary body temperature in the evening was reduced in the presence of diabetes, which was associated with autonomic neuropathy.

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References

  1. Thomas KA, Burr R, Wang SY, Lentz MJ, Shaver J (2004) Axillary and thoracic skin temperatures poorly comparable to core body temperature circadian rhythm: results from two adult populations. Biol Res Nurs 5:187–194

    Article  PubMed  Google Scholar 

  2. Ford ES (1999) Body mass index, diabetes, and C-reactive protein among US adults. Diab Care 22:1971–1977

    Article  CAS  Google Scholar 

  3. Amiya E, Watanabe M, Takata M, Watanabe S, Ozeki A, Watanabe A, Kawarasaki S, Nakao T, Hosoya Y, Omori K, Maemura K, Hirata Y, Nagai R, Komuro I (2013) Differences in body temperature variability between subjects with and without diabetes and predictive value for cardiovascular events. Circ J 77:1844–1853

    Article  PubMed  CAS  Google Scholar 

  4. Charkoudian N (2003) Skin blood flow in adult human thermoregulation: how it works, when it does not, and why. Mayo Clin Proc 78:603–612

    Article  PubMed  Google Scholar 

  5. Nishiyama K, Yasue H, Moriyama Y, Tsunoda R, Ogawa H, Yoshimura M, Kugiyama K (2001) Acute effects of melatonin administration on cardiovascular autonomic regulation in healthy men. Am Heart J 141:E9

    Article  PubMed  CAS  Google Scholar 

  6. Peschke E, Frese T, Chankiewitz E, Peschke D, Preiss U, Schneyer U, Spessert R, Muhlbauer E (2006) Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status. J Pineal Res 40:135–143

    Article  PubMed  CAS  Google Scholar 

  7. Ruiz J, Monbaron D, Parati G, Perret S, Haesler E, Danzeisen C, Hayoz D (2005) Diabetic neuropathy is a more important determinant of baroreflex sensitivity than carotid elasticity in type 2 diabetes. Hypertension 46:162–167

    Article  PubMed  CAS  Google Scholar 

  8. Champney TH, Holtorf AP, Craft CM, Reiter RJ (1986) Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections. Comp Biochem Physiol A 83:391–395

    Article  PubMed  CAS  Google Scholar 

  9. Tutuncu NB, Batur MK, Yildirir A, Tutuncu T, Deger A, Koray Z, Erbas B, Kabakci G, Aksoyek S, Erbas T (2005) Melatonin levels decrease in type 2 diabetic patients with cardiac autonomic neuropathy. J Pineal Res 39:43–49

    Article  PubMed  CAS  Google Scholar 

  10. Saini C, Morf J, Stratmann M, Gos P, Schibler U (2012) Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators. Gen Dev 26:567–580

    Article  CAS  Google Scholar 

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Acknowledgments

This research was supported by the Japan Society for the Promotion of Science through the Funding Program for World-Leading Innovative R&D on Science and Technology program.

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The authors declare no conflicts of interest.

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Authors and Affiliations

  1. Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan

    Eisuke Amiya, Masafumi Watanabe, Munenori Takata, Tomoko Nakao, Yumiko Hosoya & Issei Komuro

  2. Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan

    Shogo Watanabe

  3. Jichi Medical School, Shimotsuke, Japan

    Ryozo Nagai

Authors
  1. Eisuke Amiya
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  2. Masafumi Watanabe
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  3. Munenori Takata
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  4. Tomoko Nakao
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  5. Yumiko Hosoya
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  6. Shogo Watanabe
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  7. Ryozo Nagai
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  8. Issei Komuro
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Corresponding author

Correspondence to Masafumi Watanabe.

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Amiya, E., Watanabe, M., Takata, M. et al. Diurnal body temperature rise is reduced in diabetes with autonomic neuropathy. Clin Auton Res 24, 95–97 (2014). https://doi.org/10.1007/s10286-013-0223-9

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  • DOI: https://doi.org/10.1007/s10286-013-0223-9

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