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  1. Article

    Open Access

    The potentials of nonlinear polarization with hyperspectral imaging of RNA for hepatocellular carcinoma early diagnosis

    Most cancers acquire numerous genetic changes in proto-oncogenes as well as tumor-suppressor genes. Cancer's early diagnosis remains a challenge. Recently, nonlinear polarization has revealed the potential as ...

    Yasser H. El-Sharkawy, Sherif Elbasuney in Egyptian Journal of Medical Human Genetics (2024)

  2. Article

    Open Access

    Amygdalin-folic acid-nanoparticles inhibit the proliferation of breast cancer and enhance the effect of radiotherapy through the modulation of tumor-promoting factors/ immunosuppressive modulators in vitro

    Breast cancer (BC) cells often develop multiple mechanisms of chemo- and radio-resistance during tumor progression, which is the major reason for the failure of breast cancer therapy. Targeted nanomedicines ha...

    Mostafa A. Askar, Gharieb S. El-Sayyad in BMC Complementary Medicine and Therapies (2023)

  3. Article

    Open Access

    Multifunctional nanocomposites DDMplusAF inhibit the proliferation and enhance the radiotherapy of breast cancer cells via modulating tumor-promoting factors and metabolic reprogramming

    Tumor-promoting factors (TPF) and metabolic reprogramming are hallmarks of cancer cell growth. This study is designed to combine the newly synthesized two nanocomposites DDM (HA-FA-2DG@DCA@MgO) and AF (HA-FA-A...

    Noura M. Thabet, Mohamed K. Abdel-Rafei, Gharieb S. El-Sayyad in Cancer Nanotechnology (2022)

  4. No Access

    Article

    Nanoparticles for active combination radio mitigating agents of zinc coumarate and zinc caffeinate in a rat model

    Zinc coumarate and zinc caffeinate nanoparticles (ZnCoNPs, ZnCaNPs) affect different biological processes. This study aimed to evaluate the mitigating action of ZnCoNPs in combination with ZnCaNPs against live...

    Mostafa A. Askar, Mona S. Guida in Environmental Science and Pollution Resear… (2022)