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  1. No Access

    Article

    HPV18 oncoproteins driven expression of PKM2 reprograms HeLa cell metabolism to maintain aerobic glycolysis and viability

    The molecular basis of human papillomavirus (HPV)-mediated cellular immortalization and malignant transformation has illustrated an indispensable role of viral E6/E7-oncoproteins. However, the impact of viral-...

    Gopinath Prakasam, Mohammad Askandar Iqbal, Anusha Srivastava… in VirusDisease (2022)

  2. Article

    Open Access

    Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India

    Runt related transcription factor3 (RUNX3) is considered as a tumor suppressor gene (TSG) that functions through the TGF-β dependent apoptosis. Promoter methylation of the CpG islands of RUNX3 and overexpressi...

    Asad Ur Rehman, Mohammad Askandar Iqbal… in Cancer Cell International (2020)

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  3. Article

    Open Access

    Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition

    Warburg effect is an emerging hallmark of cancer cells with pyruvate kinase M2 (PKM2) as its key regulator. Curcumin is an extensively-studied anti-cancer compound, however, its role in affecting cancer metabo...

    Farid Ahmad Siddiqui, Gopinath Prakasam, Shilpi Chattopadhyay… in Scientific Reports (2018)

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  4. No Access

    Reference Work Entry In depth

    Pyruvate Kinase M2

    Gopinath Prakasam, Mohammad Askandar Iqbal… in Encyclopedia of Signaling Molecules (2018)

  5. No Access

    Reference Work Entry In depth

    AMP-Activated Protein Kinase (AMPK)

    Gopinath Prakasam, Mohammad Askandar Iqbal… in Encyclopedia of Signaling Molecules (2018)

  6. No Access

    Living Reference Work Entry In depth

    Pyruvate Kinase M2

    Gopinath Prakasam, Mohammad Askandar Iqbal… in Encyclopedia of Signaling Molecules

  7. No Access

    Living Reference Work Entry In depth

    AMP-Activated Protein Kinase (AMPK)

    Gopinath Prakasam, Mohammad Askandar Iqbal… in Encyclopedia of Signaling Molecules