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  1. Article

    Open Access

    Effects of age and axial length on choroidal stratified structure in normal eyes

    To quantify the choroidal structures of normal eyes by optical coherence tomography (OCT)-based binarization and evaluate the relationships among age, refractive power, and ocular axial length. This was a retr...

    Yuki Ito, Hiroaki Endo, Satoru Kase, Mitsuo Takahashi, Shozo Sonoda in Scientific Reports (2024)

  2. No Access

    Article

    Changes in choriocapillaris structure occurring in idiopathic macular hole before and after vitrectomy

    The aim of this study was to analyze the anatomical choroidal vascular layers and the changes in idiopathic macular hole (IMH) eyes over time after vitrectomy.

    Hiroaki Endo, Satoru Kase, Mitsuo Takahashi in Graefe's Archive for Clinical and Experime… (2023)

  3. No Access

    Article

    Peripapillary circulatory dysfunction precedes structural loss in treatment-naive diabetic retinopathy

    The aim of this study was to compare the timing of peripapillary vascular damage between functional and structural parameters and examine their involvement with neurovascular coupling at different stages of di...

    Mizuho Mitamura, Hiroaki Endo, Satoru Kase in Graefe's Archive for Clinical and Experime… (2023)

  4. No Access

    Article

    Choroidal vascular structures in diabetic patients: a meta-analysis

    Choroidal vascular structures are likely to be affected in diabetic patients. The aim of this study was to conduct a meta-analysis of choroidal vascular structures in diabetic eyes with no diabetic retinopathy...

    Satoru Kase, Hiroaki Endo, Mitsuo Takahashi in Graefe's Archive for Clinical and Experime… (2021)

  5. Article

    Open Access

    Factors based on optical coherence tomography correlated with vision impairment in diabetic patients

    The aim of this study is to evaluate the relationship between retinal structures and visual acuity in diabetic patients using optical coherence tomography (OCT) and OCT angiography (OCTA). This study was a ret...

    Hiroaki Endo, Satoru Kase, Hikari Tanaka, Mitsuo Takahashi in Scientific Reports (2021)

  6. No Access

    Article

    Alteration of choroidal vascular structure in diabetic macular edema

    The aim of this study was to analyze choroidal structures in healthy subjects and patients with/without diabetic macular edema (DME).

    Satoru Kase, Hiroaki Endo, Mitsuo Takahashi in Graefe's Archive for Clinical and Experime… (2020)

  7. No Access

    Article

    Relationship between choroidal structure and duration of diabetes

    The aim of this study was to evaluate the relationship between the choroidal structure of diabetic patients without diabetic retinopathy (DR) and duration of diabetes.

    Hiroaki Endo, Satoru Kase, Yuki Ito in Graefe's Archive for Clinical and Experime… (2019)

  8. No Access

    Article

    Choroidal neovascularization in a patient with blunt trauma-caused traumatic retinopathy without choroidal rupture

    To report a case of choroidal neovascularization (CNV) following blunt trauma without choroidal rupture, with past history of central serous chorioretinopathy (CSC).

    Mitsuo Takahashi, Satoshi Kinoshita in Graefe's Archive for Clinical and Experime… (2011)

  9. No Access

    Article

    Incomplete Oculomotor Palsy with Pupil Sparing Caused by Compression of the Oculomotor Nerve by a Posterior Communicating Posterior Cerebral Aneurysm

    To report a patient with agenesis of both internal carotid canals who presented with incomplete oculomotor palsy with pupil sparing.

    Mitsuo Takahashi, Manabu Kase, Yasuo Suzuki in Japanese Journal of Ophthalmology (2007)

  10. No Access

    Article

    Stark Splitting in Photoluminescence Spectra of Er in a-Si:H

    The photoluminescence spectra due to Er ions doped in a-Si:H were decomposed into several lines. The 19-K spectrum was reproduced by adding four Gaussian lines whose linewidths were increased with decreasing t...

    Minoru Kumeda, Mitsuo Takahashi, Akiharu Morimoto in MRS Online Proceedings Library (2004)

  11. No Access

    Article

    Multiple endocrine neoplasia type 1 in end-stage renal failure

    A 59-year-old woman with chronic renal failure due to type 2 diabetes mellitus (DM) is presented. Her father and a brother had a history of brain tumor. Her blood urea nitrogen and serum creatinine levels were...

    Hodaka Suzuki, Tetsuo Katoh, Yutaka Sakuma in Journal of Clinical and Experimental Nephr… (2004)

  12. No Access

    Article

    Apoptosis and microglial activation in influenza encephalopathy

    During influenza epidemics in Japan, the number of children with acute encephalopathies and encephalitis has recently increased. Although the pathophysiologies remain unclear, there is usually brain edema wit...

    Yoshiko Nakai, Masayuki Itoh, Masashi Mizuguchi, Hiroshi Ozawa in Acta Neuropathologica (2003)

  13. No Access

    Article

    Discovery of a novel serine protease inhibitor utilizing a structure-based and experimental selection of fragments technique

    We report a set of strategies to develop novel ligands (Structure Based and Experimental Selection of Fragments: SbE-SF). First, a docking simulation utilizing DOCK3.5 is performed in order to screen the fragm...

    Shingo Makino, Takashi Kayahara in Journal of Computer-Aided Molecular Design (2001)

  14. No Access

    Chapter

    Pharmacophore Model of Endothelin Antagonists

    Endothelin (ET) is a 21-amino acid peptide, and its receptor belongs to a family of Gprotein-coupled receptor. ET antagonist is expected to be a therapeutic agent for disease including myocardinal infarction, ...

    Mitsuo Takahashi, Kuniya Sakurai, Seji Niwa in Molecular Modeling and Prediction of Bioac… (2000)

  15. No Access

    Article

    Functional magnetic resonance imaging to word generation task in a patient with Broca’s aphasia

    We describe the findings of functional magnetic resonance imaging (fMRI) in a patient with Broca’s aphasia. The patient was a 45-year-old, right-handed woman who developed Broca’s aphasia after infarction in ...

    K. Miura, Yusaku Nakamura, Fumiko Miura, Ikuko Yamada in Journal of Neurology (1999)

  16. No Access

    Article

    Magnetic resonance imaging and brain-stem auditory evoked potentials in neuro-Behcet's disease

    We studied central nervous system lesions in patients with neuro-Behcet's disease using magnetic resonance imaging (MRI) of the brain and recording of brain-stem auditory evoked potentials (BAEPs). MRI reveale...

    Yusaka Nakamura, Mitsuo Takahashi, Katsuki Ueyama, Yoshiyuki Mitsui in Journal of Neurology (1994)