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Article
Open AccessEffects of age and axial length on choroidal stratified structure in normal eyes
To quantify the choroidal structures of normal eyes by optical coherence tomography (OCT)-based binarization and evaluate the relationships among age, refractive power, and ocular axial length. This was a retr...
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Article
Changes in choriocapillaris structure occurring in idiopathic macular hole before and after vitrectomy
The aim of this study was to analyze the anatomical choroidal vascular layers and the changes in idiopathic macular hole (IMH) eyes over time after vitrectomy.
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Article
Peripapillary circulatory dysfunction precedes structural loss in treatment-naive diabetic retinopathy
The aim of this study was to compare the timing of peripapillary vascular damage between functional and structural parameters and examine their involvement with neurovascular coupling at different stages of di...
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Article
Choroidal vascular structures in diabetic patients: a meta-analysis
Choroidal vascular structures are likely to be affected in diabetic patients. The aim of this study was to conduct a meta-analysis of choroidal vascular structures in diabetic eyes with no diabetic retinopathy...
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Article
Open AccessFactors based on optical coherence tomography correlated with vision impairment in diabetic patients
The aim of this study is to evaluate the relationship between retinal structures and visual acuity in diabetic patients using optical coherence tomography (OCT) and OCT angiography (OCTA). This study was a ret...
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Article
Alteration of choroidal vascular structure in diabetic macular edema
The aim of this study was to analyze choroidal structures in healthy subjects and patients with/without diabetic macular edema (DME).
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Article
Relationship between choroidal structure and duration of diabetes
The aim of this study was to evaluate the relationship between the choroidal structure of diabetic patients without diabetic retinopathy (DR) and duration of diabetes.
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Article
Choroidal neovascularization in a patient with blunt trauma-caused traumatic retinopathy without choroidal rupture
To report a case of choroidal neovascularization (CNV) following blunt trauma without choroidal rupture, with past history of central serous chorioretinopathy (CSC).
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Article
Incomplete Oculomotor Palsy with Pupil Sparing Caused by Compression of the Oculomotor Nerve by a Posterior Communicating Posterior Cerebral Aneurysm
To report a patient with agenesis of both internal carotid canals who presented with incomplete oculomotor palsy with pupil sparing.
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Article
Stark Splitting in Photoluminescence Spectra of Er in a-Si:H
The photoluminescence spectra due to Er ions doped in a-Si:H were decomposed into several lines. The 19-K spectrum was reproduced by adding four Gaussian lines whose linewidths were increased with decreasing t...
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Article
Multiple endocrine neoplasia type 1 in end-stage renal failure
A 59-year-old woman with chronic renal failure due to type 2 diabetes mellitus (DM) is presented. Her father and a brother had a history of brain tumor. Her blood urea nitrogen and serum creatinine levels were...
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Article
Apoptosis and microglial activation in influenza encephalopathy
During influenza epidemics in Japan, the number of children with acute encephalopathies and encephalitis has recently increased. Although the pathophysiologies remain unclear, there is usually brain edema wit...
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Article
Discovery of a novel serine protease inhibitor utilizing a structure-based and experimental selection of fragments technique
We report a set of strategies to develop novel ligands (Structure Based and Experimental Selection of Fragments: SbE-SF). First, a docking simulation utilizing DOCK3.5 is performed in order to screen the fragm...
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Pharmacophore Model of Endothelin Antagonists
Endothelin (ET) is a 21-amino acid peptide, and its receptor belongs to a family of Gprotein-coupled receptor. ET antagonist is expected to be a therapeutic agent for disease including myocardinal infarction, ...
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Article
Functional magnetic resonance imaging to word generation task in a patient with Broca’s aphasia
We describe the findings of functional magnetic resonance imaging (fMRI) in a patient with Broca’s aphasia. The patient was a 45-year-old, right-handed woman who developed Broca’s aphasia after infarction in ...
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Article
Magnetic resonance imaging and brain-stem auditory evoked potentials in neuro-Behcet's disease
We studied central nervous system lesions in patients with neuro-Behcet's disease using magnetic resonance imaging (MRI) of the brain and recording of brain-stem auditory evoked potentials (BAEPs). MRI reveale...