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  1. Article

    Open Access

    Core needle biopsies alter the amounts of CCR5, Siglec-15, and PD-L1 positivities in breast carcinoma

    Core needle biopsies (CNB) are widely used to diagnose breast cancer, but the procedure is invasive and thus, it changes the tumor microenvironment. The purpose of this study is to see how the expression of th...

    Minna Mutka, Kristiina Joensuu, Marja Heiskala, Mine Eray in Virchows Archiv (2023)

  2. Article

    Open Access

    Quantities of CD3+, CD8+ and CD56+ lymphocytes decline in breast cancer recurrences while CD4+ remain similar

    Much is known about tumor infiltrating lymphocytes (Tils) in primary breast cancer, as this has been the focus of much research in recent years, but regarding recurrent breast cancer, only few studies have bee...

    Minna Mutka, Kristiina Joensuu, Mine Eray, Päivi Heikkilä in Diagnostic Pathology (2023)

  3. Article

    Open Access

    Clever-1 positive macrophages in breast cancer

    Common Lymphatic Endothelial and Vascular Endothelial Receptor 1 (Clever-1) is expressed by a subset of immunosuppressive macrophages and targeting the receptor with therapeutic antibodies has been shown to ac...

    Minna Mutka, Reetta Virtakoivu, Kristiina Joensuu in Breast Cancer Research and Treatment (2022)

  4. Article

    Open Access

    Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer

    Breast cancer is now globally the most frequent cancer and leading cause of women’s death. Two thirds of breast cancers express the luminal estrogen receptor-positive (ERα + ) phenotype that is initially respo...

    Pauliina M. Munne, Lahja Martikainen, Iiris Räty, Kia Bertula in Nature Communications (2021)