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Article
Chemical constituents from the aerial parts of Melandrium firmum
Two new anthraquinones, melrubiellin C (1) and melrubiellin D (2), were isolated from the aerial parts of Melandrium firmum Rohrbach, together with eight known compounds (3–10). The structures of these compounds ...
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Article
Cytotoxic anthraquinone dimers from Melandrium firmum
Two new anthraquinone dimers, melrubiellin A (1) and melrubiellin B (2), were isolated from the aerial part of Melandrium firmum Rohrbach, along with seven known compounds (3–9). The structures of these compounds...
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Article
Inhibitory effects of (−)-loliolide on cellular senescence in human dermal fibroblasts
Cellular senescence influences tumor suppression and progress, tissue repair and regeneration, tissue and organismal aging, and age-related diseases. Aging intervention might be an advantageous target for prev...
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Article
Chemical constituents from the leaves of Juglans mandshurica
Two new (1 and 3) and two known diarylheptanoids (2 and 4), along with two tetralones (5 and 6), one naphthoquinone (7), four phenylpropanoids (8–11), and one phenol (12) were isolated from the leaves of Juglans ...
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Article
Quercetin-3-O-β-d-glucuronide isolated from Polygonum aviculare inhibits cellular senescence in human primary cells
Cellular senescence is known to contribute to tissue aging, a variety of age-related diseases, tissue regeneration, and cancer. Therefore, aging intervention might be useful for prevention of aging as well as ...
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Article
Inhibitory effects of juglanin on cellular senescence in human dermal fibroblasts
Cellular senescence contributes to tissue and organismal aging, tumor suppression and progress, tissue repair and regeneration, and age-related diseases. Thus, aging intervention might be a promising target f...
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Article
(−)-Catechin glycosides from Ulmus davidiana
Extensive chromatographic separation of the n-BuOH soluble fraction obtained from the stem and root barks of U. davidiana resulted in five hitherto unknown compounds together with a known one (−)-catechin 1. Stru...
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Article
Inhibition of DNA topoisomerases I and II of compounds from Reynoutria japonica
Three anthraquinones (1, 2 and 4), three stilbenes (5, 6 and 7) and 3,5-dihydroxybenzyl alcohol (3) were isolated from Reynoutria japonica. Their structures were identified as emodin (1), emodin-8-O-β-d-glucoside...
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Article
Discrimination of Phellodendron amurense and P. chinense based on DNA analysis and the simultaneous analysis of alkaloids
Phellodendri Cortex is the bark of the stems of Phellodendron amurense Ruprecht or P. chinense Schneider (Rutaceae), which is orginated from periderm. The internal transcribed spacer sequences of 20 originated pl...
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Article
Protective constituents against sepsis in mice from the root barks of Ulmus davidiana var. japonica
In the course of isolating preventive agents against sepsis based on the in vivo assay model, eleven known compounds, (−)-catechin (1), catechin-7-O-β-apiofuranoside (2), catechin-7-O-α-Lrhamnopyranoside (3), cat...
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Article
Orthosiphon stamineus reduces appetite and visceral fat in rats
To evaluate whether Orthosiphon stamineus (OS) reduces appetite and fat deposition, food intake and visceral fat mass following treatment with OS (450 mg/kg/day, per oral) for 2 weeks in Sprague-Dawley (SD) rats ...
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Article
Inhibition of DNA topoisomerases I and II and cytotoxicity of compounds from Ulmus davidiana var. japonica
Twenty five compounds including ten triterpenes (1–3, 5–11), six flavonoids (12–15, 24, 25), five lignans (17, 18, 21–23), two butenyl clohexnone glycosides (19–20), one fructofuranoside (16) and one fatty acid (
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Article
Topoisomerase I and II inhibitory constituents from the bark of Tilia amurensis
Two coumarins (1 and 6), one flavan-3-ol (2), one fatty acid (3), and two lignan glycosides (4 and 5) were isolated from the EtOAc and CH2Cl2 extract of the bark of Tilia amurensis. Their chemical structures were...
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Article
Chemical constituents of Melandrium firmum Rohrbach and their anti-inflammatory activity
In our ongoing search for anti-inflammatory agents originating from Korean medicinal plants, we found that the hexane and BuOH fractions of the MeOH extract from the whole plants of Melandrium firmum Rohrbach inh...
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Article
A new stilbene glucoside from the roots ofPolygonum multiflorum Thunb.
One new stillbene glucoside (6), along with five known compounds (1–5), were isolated from the roots ofPolygonum multiflorum Thumb., and their chemical structures established based on physicochemical and spectros...
