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Open AccessOVCH1 Antisense RNA 1 is differentially expressed between non-frail and frail old adults
While some old adults stay healthy and non-frail up to late in life, others experience multimorbidity and frailty often accompanied by a pro-inflammatory state. The underlying molecular mechanisms for those di...
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Open AccessAuthor Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
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Open AccessThe choice of negative control antisense oligonucleotides dramatically impacts downstream analysis depending on the cellular background
The lymphatic and the blood vasculature are closely related systems that collaborate to ensure the organism’s physiological function. Despite their common developmental origin, they present distinct functional...
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Open AccessPublisher Correction: Nanopore sequencing reveals TACC2 locus complexity and diversity of isoforms transcribed from an intronic promoter
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Open AccessDiscovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
Using the Cap Analysis of Gene Expression (CAGE) technology, the FANTOM5 consortium provided one of the most comprehensive maps of transcription start sites (TSSs) in several species. Strikingly, ~72% of them ...
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Article
Open AccessNanopore sequencing reveals TACC2 locus complexity and diversity of isoforms transcribed from an intronic promoter
Gene expression is controlled at the transcriptional and post-transcriptional levels. The TACC2 gene was known to be associated with tumors but the control of its expression is unclear. We have reported that acti...
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Open AccessThe genome sequence of Streptomyces rochei 7434AN4, which carries a linear chromosome and three characteristic linear plasmids
Streptomyces rochei 7434AN4 produces two structurally unrelated polyketide antibiotics, lankacidin and lankamycin, and carries three linear plasmids, pSLA2-L (211 kb), -M (113 kb), and -S (18 kb), whose nucleotid...
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Open AccessFANTOM5 CAGE profiles of human and mouse samples
In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expres...
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Article
Open AccessA second generation genetic linkage map of Japanese flounder (Paralichthys olivaceus)
Japanese flounder (Paralichthys olivaceus) is one of the most economically important marine species in Northeast Asia. Information on genetic markers associated with quantitative trait loci (QTL) can be used in b...
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Open AccessGenome-wide investigation of in vivoEGR-1 binding sites in monocytic differentiation
Immediate early genes are considered to play important roles in dynamic gene regulatory networks following exposure to appropriate stimuli. One of the immediate early genes, early growth response gene 1 (EGR-1), ...
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CAGE: cap analysis of gene expression