10 Result(s)
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Jordan A. Ramilowski
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Article
Open AccessEstablishment of experimental salivary gland cancer models using organoid culture and patient-derived xenografting
Depending on its histological subtype, salivary gland carcinoma (SGC) may have a poor prognosis. Due to the scarcity of preclinical experimental models, its molecular biology has so far remained largely unknow...
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Article
Open AccessAuthor Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
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Article
Open AccessThe choice of negative control antisense oligonucleotides dramatically impacts downstream analysis depending on the cellular background
The lymphatic and the blood vasculature are closely related systems that collaborate to ensure the organism’s physiological function. Despite their common developmental origin, they present distinct functional...
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Open AccessDiscovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
Using the Cap Analysis of Gene Expression (CAGE) technology, the FANTOM5 consortium provided one of the most comprehensive maps of transcription start sites (TSSs) in several species. Strikingly, ~72% of them ...
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Article
Combined inhibition of XIAP and BCL2 drives maximal therapeutic efficacy in genetically diverse aggressive acute myeloid leukemia
Aggressive therapy-resistant and refractory acute myeloid leukemia (AML) has an extremely poor outcome. By analyzing a large number of genetically complex and diverse, primary high-risk poor-outcome human AML ...
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Protocol
Low Quantity Single Strand CAGE (LQ-ssCAGE) Maps Regulatory Enhancers and Promoters
The Cap Analysis of Gene Expression (CAGE) is a powerful method to identify Transcription Start Sites (TSSs) of capped RNAs while simultaneously measuring transcripts expression level. CAGE allows map** at s...
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Article
Open AccessPredicting cell-to-cell communication networks using NATMI
Development of high throughput single-cell sequencing technologies has made it cost-effective to profile thousands of cells from diverse samples containing multiple cell types. To study how these different cel...
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Article
An atlas of human long non-coding RNAs with accurate 5′ ends
Long non-coding RNAs (lncRNAs) are largely heterogeneous and functionally uncharacterized. Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we integrate multiple transcript collections to gener...
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Article
Open AccessCorrection: Corrigendum: A draft network of ligand-receptor-mediated multicellular signalling in human
Nature Communications 6: Article number: 7866 (2015); Published: 22 July 2015; Updated: 10 February 2016. The original version of this Article contained an error in the spelling of the author Edda Kloppmann, w...
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Article
Open AccessA draft network of ligand–receptor-mediated multicellular signalling in human
Cell-to-cell communication across multiple cell types and tissues strictly governs proper functioning of metazoans and extensively relies on interactions between secreted ligands and cell-surface receptors. He...
