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Article
Effects of short-term DHEA intake on hormonal responses in young recreationally trained athletes: modulation by gender
Dehydroepiandrosterone (DHEA) figures on the World Anti-Do** Agency list of prohibited substances in sport because it is assumed that athletes expect a significant increase in testosterone through DHEA admin...
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Article
Suivi hématologique et lutte contre l’usage de la rHuEPO
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Article
Pharmacokinetics/Pharmacodynamics of Recombinant Human Erythropoietins in Do** Control
The purpose of this paper is: (i) to compare recombinant human erythropoietin (rHuEPO) pharmacokinetics in athletes and healthy individuals; and (ii) to report pharmacokinetic/pharmacodynamic (PK/PD) studies p...
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Article
Drugs for Increasing Oxygen Transport and Their Potential Use in Do**
Blood oxygenation is a fundamental factor in optimising muscular activity. Enhancement of oxygen delivery to tissues is associated with a substantial improvement in athletic performance, particularly in endura...
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Article
Pharmacokinetics of Atracurium and Laudanosine in Intensive Care Patients with Acute Respiratory Distress Syndrome Undergoing Mechanical Ventilation
Objective: To determine the pharmacokinetic profiles of atracurium and its main metabolite (laudanosine) in patients with acute respiratory distress syndrome undergoing mechanical ventilation.
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Article
Population Pharmacodynamics for Monitoring Epoetin in Athletes
Epoetin (recombinant human erythropoietin) is used by some endurance athletes to increase oxygen transport and aerobic power in an attempt to improve endurance capacity and recovery during training and competi...
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Article
Comparison of a Direct and Indirect Population Pharmacodynamic Model: Application to Recombinant Human Erythropoietin in Athletes
Basic physiologic indirect response models have been proposed to account for the pharmacodynamics of drugs that act by way of inhibition or stimulation of the production or loss of endogenous sub...
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Article
Erythropoietin abuse in athletes