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  1. Article

    Open Access

    Abfall von Sauerstoffsättigung und Blutdruck sowie Anstieg des zentralen Venendrucks im Rahmen eines Mitralklappenclip**s bei einer 81-Jährigen

    Atriumseptumdefekte (ASD) im Rahmen eines endovaskulären Mitralklappenclip**s sind potenziell hämodynamisch relevante Komplikationen. Ein sofortiger Verschluss mittels Okkluder kann eine sichere und effektiv...

    Dr. med. Martin J. Volz, Matthias Aurich, Mathias Konstandin… in Der Internist (2022)

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  2. Article

    Open Access

    COVID-19 among heart transplant recipients in Germany: a multicenter survey

    Heart transplantation may represent a particular risk factor for severe coronavirus infectious disease 2019 (COVID-19) due to chronic immunosuppression and frequent comorbidities. We conducted a nation-wide su...

    Rasmus Rivinius, Ziya Kaya, René Schramm, Udo Boeken… in Clinical Research in Cardiology (2020)

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    Article

    A novel risk score to predict survival in advanced heart failure due to cardiac amyloidosis

    Cardiac amyloidosis, caused by deposition of immunoglobulin light chains (AL) or transthyretin (ATTR), carries a poor prognosis. Established risk scores for amyloidosis may not predict outcomes in those patien...

    Michael M. Kreusser, Martin J. Volz, Benjamin Knop… in Clinical Research in Cardiology (2020)

  4. Article

    Open Access

    Benefits of peritoneal ultrafiltration in HFpEF and HFrEF patients

    Peritoneal ultrafiltration (pUF) in refractory heart failure (HF) reduces the incidence of decompensation episodes, which is of particular significance as each episode incrementally adds to mortality. Neverthe...

    Leonie Grossekettler, Bastian Schmack, Carsten Brockmann… in BMC Nephrology (2020)

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  5. No Access

    Article

    Implementation of an intensified outpatient follow-up protocol improves outcomes in patients with ventricular assist devices

    Ventricular assist devices (VAD) are increasingly used as long-term treatment for advanced heart failure. However, survival after VAD implantation is still unsatisfactory, and no specific outpatient follow-up ...

    Sonja Hamed, Bastian Schmack, Florian Mueller… in Clinical Research in Cardiology (2019)

  6. No Access

    Article

    Invasive hemodynamics and cardiac biomarkers to predict outcomes after percutaneous edge-to-edge mitral valve repair in patients with severe heart failure

    Percutaneous mitral valve repair (PMVR) via MitraClip implantation is a therapeutic option for high-risk or non-surgical candidates with severe mitral regurgitation (MR) and advanced stages of heart failure (H...

    Michael M. Kreusser, Nicolas A. Geis, Nicolas Berlin… in Clinical Research in Cardiology (2019)

  7. No Access

    Chapter

    Inpatient Therapeutic Options

    Patients with acute dyspnea resulting from acute heart failure should be rapidly assessed and stabilized. First, patients should be put in a seated posture and, if necessary, supplemental oxygen and ventilator...

    Michael M. Kreusser, Philip W. Raake in Heart Failure (2019)

  8. No Access

    Article

    A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway

    A proteolytically derived fragment of the epigenetic regulator HDAC4 protects the heart through transcriptional repression of the hexosamine biosynthetic pathway, thereby inhibiting protein O-GlcNAcylation and...

    Lorenz H Lehmann, Zegeye H Jebessa, Michael M Kreusser, Axel Horsch… in Nature Medicine (2018)

  9. No Access

    Article

    Inducible cardiomyocyte-specific deletion of CaM kinase II protects from pressure overload-induced heart failure

    CaM kinase II (CaMKII) has been suggested to drive pathological cardiac remodeling and heart failure. However, the evidence provided so far is based on inhibitory strategies using chemical compounds and peptid...

    Michael M. Kreusser, Lorenz H. Lehmann, Nora Wolf… in Basic Research in Cardiology (2016)