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Open AccessThird dose of the BNT162b2 vaccine in cardiothoracic transplant recipients: predictive factors for humoral response
We report the results of a prospective study on the immunogenicity of a 3rd dose of BNT162b2 in thoracic organ recipients with no or minimal response following a two-dose BNT162b2 vaccination scheme.
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Open AccessAkzeptanz einer telemetrischen Versorgung bei Patienten mit sICD-Sicherheitshinweis
Telemonitoring dient der Überwachung von implantierbaren Kardioverter-Defibrillatoren (ICD). Trotz der wissenschaftlich nachgewiesenen Effektivität und Sicherheit der telemetrischen Versorgung zeigen Studien, ...
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Open AccessCorrection to: Five-year results of heart rate control with ivabradine or metoprolol succinate in patients after heart transplantation
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Open AccessFive-year results of heart rate control with ivabradine or metoprolol succinate in patients after heart transplantation
Cardiac graft denervation causes inadequate sinus tachycardia in patients after heart transplantation (HTX) which is associated with reduced survival. This study investigated the 5-year results of heart rate c...
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Open AccessPoor humoral and T-cell response to two-dose SARS-CoV-2 messenger RNA vaccine BNT162b2 in cardiothoracic transplant recipients
Immunocompromised patients have been excluded from studies of SARS-CoV-2 messenger RNA vaccines. The immune response to vaccines against other infectious agents has been shown to be blunted in such patients. W...
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Epigenetic regulation of cardiac electrophysiology in atrial fibrillation: HDAC2 determines action potential duration and suppresses NRSF in cardiomyocytes
Atrial fibrillation (AF) is associated with electrical remodeling, leading to cellular electrophysiological dysfunction and arrhythmia perpetuation. Emerging evidence suggests a key role for epigenetic mechani...
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Open AccessCOVID-19 among heart transplant recipients in Germany: a multicenter survey
Heart transplantation may represent a particular risk factor for severe coronavirus infectious disease 2019 (COVID-19) due to chronic immunosuppression and frequent comorbidities. We conducted a nation-wide su...
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Control of cardiac chronotropic function in patients after heart transplantation: effects of ivabradine and metoprolol succinate on resting heart rate in the denervated heart
Patients after heart transplantation (HTX) present with sinus tachycardia due to graft denervation. As elevated heart rates negatively affect survival, the aim of this study was to analyze the effects of ivabr...
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Article
Open AccessSubtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells
Human induced pluripotent stem cells (hiPSC) harbor the potential to differentiate into diverse cardiac cell types. Previous experimental efforts were primarily directed at the generation of hiPSC-derived cell...
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Open AccessFeasibility Study on Cardiac Arrhythmia Ablation Using High-Energy Heavy Ion Beams
High-energy ion beams are successfully used in cancer therapy and precisely deliver high doses of ionizing radiation to small deep-seated target volumes. A similar noninvasive treatment modality for cardiac ar...
