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Article
Following the signal sequence from ribosomal tunnel exit to signal recognition particle
Membrane and secretory proteins can be co-translationally inserted into or translocated across the membrane1. This process is dependent on signal sequence recognition on the ribosome by the signal recognition par...
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Article
Structure of eEF3 and the mechanism of transfer RNA release from the E-site
Elongation factor eEF3 is an ATPase that, in addition to the two canonical factors eEF1A and eEF2, serves an essential function in the translation cycle of fungi. eEF3 is required for the binding of the aminoa...
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Article
ERj1p uses a universal ribosomal adaptor site to coordinate the 80S ribosome at the membrane
Ribosomes translating secretory and membrane proteins are targeted to the endoplasmic reticulum membrane and attach to the protein-conducting channel and ribosome-associated membrane proteins (RAMPs). Recently...